Literature DB >> 25696372

'Brugada ECG' elicited by imipramine overdose.

M P van den Berg, J E Tulleken, A A M Wilde.   

Abstract

The ECG hallmark of the Brugada syndrome is ST-segment elevation in the right precordial leads. However, a 'Brugada ECG' may also occasionally be caused by other conditions. We report a case of a Brugada ECG due to an overdose of imipramine, a tricyclic antidepressant. The patient, a 66-year-old woman, was admitted to the emergency unit in a comatose state, due to autointoxication with imipramine. In addition to other signs of massive sodium-channel blockade, the ECG showed typical ST-segment elevation in the right precordial and the inferior leads. The abnormalities resolved quickly after administration of sodium bicarbonate.

Entities:  

Keywords:  Brugada syndrome; ST-segment elevation; imipramine overdose

Year:  2004        PMID： 25696372      PMCID： PMC2497168     

Source DB:  PubMed          Journal:  Neth Heart J        ISSN： 1568-5888            Impact factor:   2.380


  8 in total

1.  Transient ST segment elevation in right precordial leads induced by psychotropic drugs: relationship to the Brugada syndrome.

Authors:  F Rouleau; P Asfar; S Boulet; L Dube; J M Dupuis; P Alquier; J Victor
Journal:  J Cardiovasc Electrophysiol       Date:  2001-01

2.  Overdose of cyclic antidepressants and the Brugada syndrome.

Authors:  Dany Goldgran-Toledano; Georgios Sideris; Jean-Philippe Kevorkian
Journal:  N Engl J Med       Date:  2002-05-16       Impact factor: 91.245

Review 3.  Proposed diagnostic criteria for the Brugada syndrome: consensus report.

Authors:  Arthur A M Wilde; Charles Antzelevitch; Martin Borggrefe; Josep Brugada; Ramón Brugada; Pedro Brugada; Domenico Corrado; Richard N W Hauer; Robert S Kass; Koonlawee Nademanee; Silvia G Priori; Jeffrey A Towbin
Journal:  Circulation       Date:  2002-11-05       Impact factor: 29.690

4.  QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome.

Authors:  Maria Vittoria Pitzalis; Matteo Anaclerio; Massimo Iacoviello; Cinzia Forleo; Pietro Guida; Rossella Troccoli; Francesco Massari; Filippo Mastropasqua; Sandro Sorrentino; Andrea Manghisi; Paolo Rizzon
Journal:  J Am Coll Cardiol       Date:  2003-11-05       Impact factor: 24.094

5.  Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

Authors:  Franck Potet; Philippe Mabo; Guillaume Le Coq; Vincent Probst; Jean-Jacques Schott; Fabrice Airaud; Gilles Guihard; Jean-Claude Daubert; Denis Escande; Hervé Le Marec
Journal:  J Cardiovasc Electrophysiol       Date:  2003-02

6.  Abnormal ventricular repolarization mimicking myocardial infarction after heterocyclic antidepressant overdose.

Authors:  R Bolognesi; D Tsialtas; P Vasini; M Conti; C Manca
Journal:  Am J Cardiol       Date:  1997-01-15       Impact factor: 2.778

Review 7.  Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.

Authors:  J B Marshall; A D Forker
Journal:  Am Heart J       Date:  1982-03       Impact factor: 4.749

8.  Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report.

Authors:  P Brugada; J Brugada
Journal:  J Am Coll Cardiol       Date:  1992-11-15       Impact factor: 24.094
  8 in total
  1 in total

Review 1.  Computational approaches to understand cardiac electrophysiology and arrhythmias.

Authors:  Byron N Roberts; Pei-Chi Yang; Steven B Behrens; Jonathan D Moreno; Colleen E Clancy
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-08-10       Impact factor: 4.733
  1 in total

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