Katharine E Brock1, James Wall2, Micaela Esquivel3, Beverley Newman4, Neyssa Marina5, Craig Albanese2, Florette K Hazard6. 1. Stanford University School of Medicine, Department of Pediatrics Division of Pediatric Hematology/Oncology kebrock@stanford.edu. 2. Department of Surgery, Division of Pediatric Surgery. 3. Department of Surgery. 4. Department of Radiology and. 5. Stanford University School of Medicine, Department of Pediatrics Division of Pediatric Hematology/Oncology. 6. Stanford University School of Medicine, Department of Pediatrics Department of Pathology, Stanford, CA, USA.
Abstract
BACKGROUND: Congenital peribronchial myofibroblastic tumor (CPMT) is a rare, benign lung tumor of infants, with only 19 reported cases worldwide. It is often diagnosed by prenatal imaging or in the immediate postnatal period due to co-morbidities like polyhydramnios, fetal hydrops, respiratory distress, and heart failure. OBSERVATION: We report the oldest known infant (8 weeks old) diagnosed with CPMT, and present his clinical course including the relevant radiographic and histopathologic findings. CONCLUSIONS: CPMT is a rare tumor that should be considered among other primary lung tumors of infancy (developmental, benign, and malignant) even if not detected prenatally or in the immediate postnatal period.
BACKGROUND:Congenital peribronchial myofibroblastic tumor (CPMT) is a rare, benign lung tumor of infants, with only 19 reported cases worldwide. It is often diagnosed by prenatal imaging or in the immediate postnatal period due to co-morbidities like polyhydramnios, fetal hydrops, respiratory distress, and heart failure. OBSERVATION: We report the oldest known infant (8 weeks old) diagnosed with CPMT, and present his clinical course including the relevant radiographic and histopathologic findings. CONCLUSIONS: CPMT is a rare tumor that should be considered among other primary lung tumors of infancy (developmental, benign, and malignant) even if not detected prenatally or in the immediate postnatal period.
Authors: Stephan L Waelti; Laurent Garel; Dorothée Dal Soglio; Françoise Rypens; Michael Messerli; Josée Dubois Journal: Pediatr Radiol Date: 2017-09-07