Literature DB >> 2569553

S-methylation in motorneuron disease and Parkinson's disease.

R H Waring1, G B Steventon, S G Sturman, M T Heafield, M C Smith, A C Williams.   

Abstract

Thiolmethyltransferase activity has been measured in newly diagnosed, untreated patients with idiopathic Parkinson's disease and motorneuron disease, and in normal volunteers. In Parkinsonian patients, mean thiolmethyltransferase activity was low (300 U/mg protein [SD 96]) compared with that in controls (947 [409]), whereas activity was high in patients with motorneuron disease (2077 [825]).

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Year:  1989        PMID: 2569553     DOI: 10.1016/s0140-6736(89)90538-2

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  11 in total

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Authors:  A C Williams; G B Steventon; S Sturman; R H Waring
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