| Literature DB >> 25695366 |
Nathan J Gesmundo1, Jean-Marc M Grandjean, David A Nicewicz.
Abstract
In this work we present a direct catalytic synthesis of γ-lactams and pyrrolidines from alkenes and activated unsaturated amides or protected unsaturated amines, respectively. Using a mesityl acridinium single electron photooxidant and a thiophenol cocatalyst under irradiation, we are able to directly forge these important classes of heterocycles with complete regiocontrol.Entities:
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Year: 2015 PMID： 25695366 DOI： 10.1021/acs.orglett.5b00316
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005