Literature DB >> 25695316

Synthesis of substituted resorcinol monomethyl ethers from 2-bromo-3-methoxycyclohex-2-en-1-ones.

Wenjie Shao1, Derrick L J Clive1.   

Abstract

2-Bromo-3-methoxycyclohex-2-en-1-ones are readily alkylated at C-6 with reactive halides, and then treatment with DBU (2 equiv) in PhMe at room temperature results in smooth loss of bromide and aromatization to resorcinol monomethyl ethers of defined substitution pattern.

Entities:  

Year:  2015        PMID: 25695316     DOI: 10.1021/acs.joc.5b00192

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

Review 1.  Total Synthesis of Anti-MRSA Active Diorcinols and Analogues.

Authors:  G Jacob Boehlich; Jessica de Vries; Olivia Geismar; Mirja Gudzuhn; Wolfgang R Streit; Sebastian G Wicha; Nina Schützenmeister
Journal:  Chemistry       Date:  2020-07-01       Impact factor: 5.236

  1 in total

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