Literature DB >> 25694751

Management and investigation of viral gastroenteritis nosocomial outbreaks: lessons learned from a recent outbreak, Greece, 2012.

T Sideroglou1, F Kontopidou2, K Mellou1, A Maragos2, M Potamiti-Komi1, T Gerakis3, E Vogiatzakis3, A Pefanis3, T Georgakopoulou1, Hc Maltezou2.   

Abstract

BACKGROUND: A nosocomial outbreak in a 740-bed hospital in Athens, Greece, was investigated in January-February 2012.
METHODS: Recommendations on infection control measures were given and two case-control studies were conducted among patients (study A) and health care workers (HCWs) (study B). Compliance to control measures was evaluated.
RESULTS: The absence of a routine recording system of nosocomial-acquired gastroenteritis cases led to a 10 days delay in outbreak identification. In total, 63 gastroenteritis cases were identified; 30 HCWs and 33 patients. In the multivariable analysis of study A the disease incidence among patients was statistical significantly associated with a prior incident of vomitus in their room (OR=7.96, 95% CI=1.29-49.2). In study B, the incidence was associated with the history of direct contact with a symptomatic patient (OR=3.03, 95%CI 1.01-9.12). Twenty one (75%) of the symptomatic HCWs reported absence from work for a median of 2 days (range: 1-4). Seven (25.0%) continued to work despite being symptomatic. Only, 11.1% of patients were isolated or cohorted after developing symptoms. In-hospital virological testing was not feasible and one specimen sent to a university laboratory was positive for norovirus.
CONCLUSIONS: An appropriately designed protocol regarding the detection, the management and the laboratory investigation of nosocomial gastroenteritis outbreaks should be followed in order effective containment to be reassured. Hippokratia 2014; 18 (3): 204-208.

Entities:  

Keywords:  gastroenteritis; hospital; norovirus; nosocomial; outbreak

Year:  2014        PMID: 25694751      PMCID: PMC4309137     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


  22 in total

1.  Epidemiologic and molecular trends of "Norwalk-like viruses" associated with outbreaks of gastroenteritis in the United States.

Authors:  Rebecca L Fankhauser; Stephan S Monroe; Jacqueline S Noel; Charles D Humphrey; Joseph S Bresee; Umesh D Parashar; Tamie Ando; Roger I Glass
Journal:  J Infect Dis       Date:  2002-06-10       Impact factor: 5.226

Review 2.  Infection control measures for norovirus: a systematic review of outbreaks in semi-enclosed settings.

Authors:  J P Harris; B A Lopman; S J O'Brien
Journal:  J Hosp Infect       Date:  2009-10-12       Impact factor: 3.926

Review 3.  Healthcare epidemiology: gastrointestinal flu: norovirus in health care and long-term care facilities.

Authors:  Maria A Said; Trish M Perl; Cynthia L Sears
Journal:  Clin Infect Dis       Date:  2008-11-01       Impact factor: 9.079

4.  Impact of an outbreak of norovirus infection on hospital resources.

Authors:  Walter Zingg; Carlo Colombo; Thomas Jucker; Walter Bossart; Christian Ruef
Journal:  Infect Control Hosp Epidemiol       Date:  2005-03       Impact factor: 3.254

5.  Updated norovirus outbreak management and disease prevention guidelines.

Authors: 
Journal:  MMWR Recomm Rep       Date:  2011-03-04

6.  Epidemiology of Norwalk-like human caliciviruses in hospital outbreaks of acute gastroenteritis in the Stockholm area in 1996.

Authors:  M Billgren; B Christenson; K-O Hedlund; J Vinjé
Journal:  J Infect       Date:  2002-01       Impact factor: 6.072

7.  25- to 30-nm virus particle associated with a hospital outbreak of acute gastroenteritis with evidence for airborne transmission.

Authors:  L A Sawyer; J J Murphy; J E Kaplan; P F Pinsky; D Chacon; S Walmsley; L B Schonberger; A Phillips; K Forward; C Goldman
Journal:  Am J Epidemiol       Date:  1988-06       Impact factor: 4.897

8.  Hyperemesis hiemis--a sick hazard.

Authors:  E O Caul
Journal:  J Hosp Infect       Date:  1995-06       Impact factor: 3.926

9.  Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003.

Authors:  Ben A Lopman; Mark H Reacher; Ian B Vipond; Dawn Hill; Christine Perry; Tracey Halladay; David W Brown; W John Edmunds; Joyshri Sarangi
Journal:  Emerg Infect Dis       Date:  2004-10       Impact factor: 6.883

10.  Host, weather and virological factors drive norovirus epidemiology: time-series analysis of laboratory surveillance data in England and Wales.

Authors:  Ben Lopman; Ben Armstrong; Christina Atchison; Jim J Gray
Journal:  PLoS One       Date:  2009-08-24       Impact factor: 3.240

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  2 in total

1.  Associations of infection control measures and norovirus outbreak outcomes in healthcare settings: a systematic review and meta-analysis.

Authors:  Carly Adams; Shenita R Peterson; Aron J Hall; Umesh Parashar; Benjamin A Lopman
Journal:  Expert Rev Anti Infect Ther       Date:  2021-08-04       Impact factor: 5.091

Review 2.  Significance of norovirus in occupational health: a review of published norovirus outbreaks in Central and Northern Europe.

Authors:  Felix Martin Hofmann; Edward Olawumi; Martina Michaelis; Ulrich Stößel; Friedrich Hofmann
Journal:  Int Arch Occup Environ Health       Date:  2020-05-01       Impact factor: 3.015

  2 in total

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