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Literature DB >> 25693927

Recent advances of histone modification in gastric cancer.

Wen-Yan Yang, Jing-Liang Gu, Tian-Min Zhen¹.

Abstract

Epigenetics play important roles during development progress of tumor. The histone modifications are the most important constituted field. Recently, accumulating research focused on exploring the roles of those modifications in regulating tumorigenesis. Moreover, the dysregulation of histone modifications is supposed to have vital clinical significance. Numerous histone modifications have the potential to be prognostic biomarkers, monitoring response of therapy, early diagnostic markers. Herein, we review the recent advances of histone modifications involving development of gastric cancer.

Entities: Disease

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Year: 2014 PMID： 25693927 DOI： 10.4103/0973-1482.151450

Source DB: PubMed Journal: J Cancer Res Ther ISSN： 1998-4138 Impact factor: 1.805

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Cited

13 in total

1. Inhibition of histone/lysine acetyltransferase activity kills CoCl₂-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness.

Authors: Suvasmita Rath; Lopamudra Das; Shrikant Babanrao Kokate; Nilabh Ghosh; Pragyesh Dixit; Niranjan Rout; Shivaram P Singh; Subhasis Chattopadhyay; Hassan Ashktorab; Duane T Smoot; Mahadeva M Swamy; Tapas K Kundu; Sheila E Crowe; Asima Bhattacharyya
Journal: Int J Biochem Cell Biol Date: 2016-11-23 Impact factor: 5.085

Recent advances of histone modification in gastric cancer.

1. Inhibition of histone/lysine acetyltransferase activity kills CoCl₂-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness.

2. AKT inhibits the phosphorylation level of H2A at Tyr57 via CK2α to promote the progression of gastric cancer.

3. Methylation Patterns of Lys9 and Lys27 on Histone H3 Correlate with Patient Outcome in Gastric Cancer.

4. The expression and significance of histone lysine methylation in endometrial cancer.

5. Expression profiles of histone modification genes in gastric cancer progression.

Review 6. Challenges of deciphering gastric cancer heterogeneity.

7. Expression pattern of histone lysine-specific demethylase 6B in gastric cancer.

Review 8. Gastric cancer and related epigenetic alterations.

9. DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.

Review 10. Histone Modifications and their Role in Colorectal Cancer (Review).