Literature DB >> 25693441

[Management of the potential organ donor].

Guillermo Bugedo, Sebastián Bravo, Carlos Romero, Ricardo Castro.   

Abstract

Solid organ transplantation is limited by donor availability. The loss of brain function produces hemodynamic, respiratory, hormonal and metabolic changes that lead to hypotension and organ dysfunction. Management of a potential donor is similar to any critically ill patient. Cardiovascular stability and protective ventilatory support must be pursued, aimed at minimizing the local and systemic inflammatory response that is triggered by brain death. There is no consensus on protocols for hormonal supplementation. The administration of vasopressin analogues and steroids may be beneficial under certain conditions. Appropriate medical management helps to optimize the function of different organs prior to transplantation. This may increase the number of harvested organs and improve their functional outcome in the recipient.

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Year:  2014        PMID: 25693441     DOI: 10.4067/S0034-98872014001200012

Source DB:  PubMed          Journal:  Rev Med Chil        ISSN: 0034-9887            Impact factor:   0.553


  1 in total

1.  Impact of implementing a protocol of respiratory care measures and optimization of mechanical ventilation in potential lung donors.

Authors:  Marco Guillermo Bezzi; Carla Candela Brovia; Juan Manuel Carballo; Maia Inés Elías; Agustina Belén Moreno; Vanesa Romina Ruiz; Fernanda Cordiviola; David Barbieri; Adriana Fariña; Silvina Borello
Journal:  Rev Bras Ter Intensiva       Date:  2020 Oct-Dec
  1 in total

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