Literature DB >> 25692658

Native fluorescence spectroscopy of blood plasma of rats with experimental diabetes: identifying fingerprints of glucose-related metabolic pathways.

Evgeny Shirshin1, Olga Cherkasova2, Tatiana Tikhonova3, Elena Berlovskaya1, Alexander Priezzhev4, Victor Fadeev1.   

Abstract

We present the results of a native fluorescence spectroscopy study of blood plasma of rats with experimental diabetes. It was shown that the fluorescence emission band shape at 320 nm excitation is the most indicative of hyperglycemia in the blood plasma samples. We provide the interpretation of this fact based on the changes in reduced nicotinamide adenine dinucleotide phosphate concentration due to glucose-related metabolic pathways and protein fluorescent cross-linking formation following nonenzymatic glycation.

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Year:  2015        PMID： 25692658     DOI： 10.1117/1.JBO.20.5.051033

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN： 1083-3668            Impact factor:   3.170


  4 in total

1.  Bayesian network model for identification of pathways by integrating protein interaction with genetic interaction data.

Authors:  Changhe Fu; Su Deng; Guangxu Jin; Xinxin Wang; Zu-Guo Yu
Journal:  BMC Syst Biol       Date:  2017-09-21

2.  Two-photon autofluorescence lifetime imaging of human skin papillary dermis in vivo: assessment of blood capillaries and structural proteins localization.

Authors:  Evgeny A Shirshin; Yury I Gurfinkel; Alexander V Priezzhev; Victor V Fadeev; Juergen Lademann; Maxim E Darvin
Journal:  Sci Rep       Date:  2017-04-26       Impact factor: 4.379

3.  The Oxidation-Induced Autofluorescence Hypothesis: Red Edge Excitation and Implications for Metabolic Imaging.

Authors:  Alexey N Semenov; Boris P Yakimov; Anna A Rubekina; Dmitry A Gorin; Vladimir P Drachev; Mikhail P Zarubin; Alexander N Velikanov; Juergen Lademann; Victor V Fadeev; Alexander V Priezzhev; Maxim E Darvin; Evgeny A Shirshin
Journal:  Molecules       Date:  2020-04-17       Impact factor: 4.411

4.  A Rapid Method to Measure Serum Retinol Concentrations in Japanese Black Cattle Using Multidimensional Fluorescence.

Authors:  Yoshio Tamura; Hiroki Inoue; Satoshi Takemoto; Kazuo Hirano; Kazutoshi Miyaura
Journal:  J Fluoresc       Date:  2020-10-22       Impact factor: 2.217
  4 in total

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