Literature DB >> 25692267

Evidence update on prevention of surgical site infection.

David Leaper1, Karen Ousey.   

Abstract

PURPOSE OF REVIEW: Surgical site infection (SSI) is a common healthcare-associated infection and complicates up to 10-20% of operations with considerable strain on healthcare resources. Apart from the widely adopted use of appropriate hair removal, antibiotic prophylaxis, avoidance of hypothermia and perioperative glycaemic control to reduce SSIs, this review has considered new research and systematic reviews, and whether their findings should be included in guidelines. RECENT
FINDINGS: The efficacy of preoperative bathing/showering, antibiotic prophylaxis for clean surgery and perioperative oxygen supplementation to reduce the risk of SSI is still in doubt. By contrast, the use of 2% chlorhexidine in alcohol skin preparation, postoperative negative pressure wound therapy and antiseptic surgical dressings do show promise. Antimicrobial sutures in independent meta-analyses were found to reduce the risk of SSI after all classes of surgery (except dirty) whereas the use of wound guards, or diathermy skin incision (compared with scalpel incision), did not.
SUMMARY: The incidence of SSI after surgery is not falling. Based on this review of published trials and evidence-based systematic reviews some advances might be included into these care bundles. More research is needed together with improved compliance with care bundles.

Entities:  

Mesh:

Year:  2015        PMID: 25692267     DOI: 10.1097/QCO.0000000000000144

Source DB:  PubMed          Journal:  Curr Opin Infect Dis        ISSN: 0951-7375            Impact factor:   4.915


  17 in total

Review 1.  Chlorhexidine: Patient Bathing and Infection Prevention.

Authors:  Salma Abbas; Sangeeta Sastry
Journal:  Curr Infect Dis Rep       Date:  2016-08       Impact factor: 3.725

2.  The impact of operative time and hypothermia in acute burn surgery.

Authors:  N Ziolkowski; A D Rogers; W Xiong; B Hong; S Patel; B Trull; M G Jeschke
Journal:  Burns       Date:  2017-10-28       Impact factor: 2.744

3.  The Role of Topical Antiseptic Agents Within Antimicrobial Stewardship Strategies for Prevention and Treatment of Surgical Site and Chronic Open Wound Infection.

Authors:  Christopher D Roberts; David J Leaper; Ojan Assadian
Journal:  Adv Wound Care (New Rochelle)       Date:  2017-02-01       Impact factor: 4.730

Review 4.  The role of antimicrobial sutures in preventing surgical site infection.

Authors:  D Leaper; P Wilson; O Assadian; C Edmiston; M Kiernan; A Miller; G Bond-Smith; J Yap
Journal:  Ann R Coll Surg Engl       Date:  2017-07       Impact factor: 1.891

Review 5.  Re-examining causes of surgical site infections following elective surgery in the era of asepsis.

Authors:  John C Alverdy; Neil Hyman; Jack Gilbert
Journal:  Lancet Infect Dis       Date:  2020-01-29       Impact factor: 25.071

Review 6.  [Prevention of postoperative surgical site infections : Between tradition and evidence].

Authors:  S Scheithauer; T Artelt; M Bauer; R M Waeschle
Journal:  Anaesthesist       Date:  2016-05-04       Impact factor: 1.041

7.  Surgical site infections in neonates are independently associated with longer hospitalizations.

Authors:  E A Gilje; M J Hossain; C D Vinocur; L Berman
Journal:  J Perinatol       Date:  2017-07-27       Impact factor: 2.521

8.  Postoperative Complications of Free Flap Reconstruction in Moderate-Advanced Head and Neck Squamous Cell Carcinoma: A Prospective Cohort Study Based on Real-World Data.

Authors:  Delong Li; Chong Wang; Wei Wei; Bo Li; Huan Liu; Aoming Cheng; Qifang Niu; Zhengxue Han; Zhien Feng
Journal:  Front Oncol       Date:  2022-06-24       Impact factor: 5.738

9.  A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgery.

Authors:  Elliott Bennett-Guerrero; Harold S Minkowitz; Alvaro M Segura-Vasi; Jorge E Marcet; Jennifer A White; G Ralph Corey; Kent S Allenby
Journal:  Perioper Med (Lond)       Date:  2016-06-16

10.  Optimizing Prophylactic Antibiotic Practice for Cardiothoracic Surgery by Pharmacists' Effects.

Authors:  Ling Zhou; Jingjing Ma; Jie Gao; Shiqi Chen; Jianan Bao
Journal:  Medicine (Baltimore)       Date:  2016-03       Impact factor: 1.889

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