Literature DB >> 25691082

A cadaveric feasibility study of the intraorbital cannula injections of hyaluronidase for initial salvation of the ophthalmic artery occlusion.

Tanvaa Tansatit1, Prawit Apinuntrum, Thavorn Phetudom.   

Abstract

BACKGROUND: Phthisis bulbi may follow cosmetic filler injections. Early attempts to inject hyaluronidase into the orbit after detection of devastating signs and symptoms may potentially mitigate the complications.
METHODS: Cannula routes along the orbital walls were studied. Depths of injections were determined in 30 dry skulls. Deep cannula insertions were carefully performed while avoiding exiting the orbit. Forty-six cadaveric orbits with intravascular latex injection were dissected to determine injection techniques, to verify structures at risk along the routes, and to evaluate substance dispersion.
RESULTS: The limited depths of the superior, lateral, medial, and inferior injection routes were 4.2, 3.8, 3.6, and 2.5 cm respectively, while the orbital width was 3.9 cm. The superior parasagittal injection was effective and rarely tears the superior ophthalmic vein, artery, and the optic nerve. The medial injection should be avoided because it may injure the lacrimal sac, the ophthalmic artery, and the optic nerve. Without limited depth, the lateral injection may damage the lacrimal gland and artery and proceeds to damage the optic nerve. The inferior parasagittal injection tends to exit into the infratemporal fossa but the inferior oblique injection may be safer and effective but more complicate with the depth of 4.2 cm.
CONCLUSION: The superior parasagittal injection is a recommended simple technique with a minimal chance of vascular injury. The inferior oblique injection requires more skill but it may be safer because of the lower position. For safety reasons, depth of each cannula insertion should not exceed the orbital width. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern BasicScience, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors http://www.springer.com/00266.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25691082     DOI: 10.1007/s00266-015-0456-1

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  2 in total

1.  Prevention and management of vision loss relating to facial filler injections.

Authors:  Kwok Thye David Loh; Jun Jin Chua; Hung Ming Lee; Joyce Teng-Ee Lim; Gerard Chuah; Benjamin Yim; Boon Kwang Puah
Journal:  Singapore Med J       Date:  2016-08       Impact factor: 1.858

2.  Periorbital Injectables: Understanding and Avoiding Complications.

Authors:  Catherine J Hwang
Journal:  J Cutan Aesthet Surg       Date:  2016 Apr-Jun
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.