Bridget Kelly1, Kathleen C Ostapkovich2, Collin Weinberger1, Valentin Fuster3. 1. Institute of Medicine of the National Academies, Washington, DC, USA. 2. Institute of Medicine of the National Academies, Washington, DC, USA; George Washington University School of Medicine and Health Sciences, Washington, DC, USA. 3. Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY, USA.