Literature DB >> 25688402

Mining the genomes of exceptional responders.

David K Chang1, Sean M Grimmond2, T R Jeffry Evans3, Andrew V Biankin4.   

Abstract

The National Cancer Institute of the United States recently announced a major new initiative in understanding the genomes or, more broadly, the molecular phenotypes of exceptional responders. What can we expect to learn from exceptional responders? What are the potential benefits, and how do we approach studying them?

Entities:  

Mesh:

Year:  2014        PMID: 25688402     DOI: 10.1038/nrc3723

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  6 in total

1.  'Basket studies' will hold intricate data for cancer drug approvals.

Authors:  Cassandra Willyard
Journal:  Nat Med       Date:  2013-06       Impact factor: 53.440

2.  The Cancer Genome Atlas Pan-Cancer analysis project.

Authors:  John N Weinstein; Eric A Collisson; Gordon B Mills; Kenna R Mills Shaw; Brad A Ozenberger; Kyle Ellrott; Ilya Shmulevich; Chris Sander; Joshua M Stuart
Journal:  Nat Genet       Date:  2013-10       Impact factor: 38.330

3.  Genome sequencing identifies a basis for everolimus sensitivity.

Authors:  Gopa Iyer; Aphrothiti J Hanrahan; Matthew I Milowsky; Hikmat Al-Ahmadie; Sasinya N Scott; Manickam Janakiraman; Mono Pirun; Chris Sander; Nicholas D Socci; Irina Ostrovnaya; Agnes Viale; Adriana Heguy; Luke Peng; Timothy A Chan; Bernard Bochner; Dean F Bajorin; Michael F Berger; Barry S Taylor; David B Solit
Journal:  Science       Date:  2012-08-23       Impact factor: 47.728

4.  Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

Authors:  Angela Chou; Nicola Waddell; Mark J Cowley; Anthony J Gill; David K Chang; Ann-Marie Patch; Katia Nones; Jianmin Wu; Mark Pinese; Amber L Johns; David K Miller; Karin S Kassahn; Adnan M Nagrial; Harpreet Wasan; David Goldstein; Christopher W Toon; Venessa Chin; Lorraine Chantrill; Jeremy Humphris; R Scott Mead; Ilse Rooman; Jaswinder S Samra; Marina Pajic; Elizabeth A Musgrove; John V Pearson; Adrienne L Morey; Sean M Grimmond; Andrew V Biankin
Journal:  Genome Med       Date:  2013-08-31       Impact factor: 11.117

5.  Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise.

Authors:  William T Riley; Russell E Glasgow; Lynn Etheredge; Amy P Abernethy
Journal:  Clin Transl Med       Date:  2013-05-10

6.  Fool's gold, lost treasures, and the randomized clinical trial.

Authors:  David J Stewart; Razelle Kurzrock
Journal:  BMC Cancer       Date:  2013-04-16       Impact factor: 4.430

  6 in total
  16 in total

1.  Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.

Authors:  Timothy N Phoenix; Deanna M Patmore; Scott Boop; Nidal Boulos; Megan O Jacus; Yogesh T Patel; Martine F Roussel; David Finkelstein; Liliana Goumnerova; Sebastien Perreault; Elizabeth Wadhwa; Yoon-Jae Cho; Clinton F Stewart; Richard J Gilbertson
Journal:  Cancer Cell       Date:  2016-03-31       Impact factor: 31.743

2.  Pathogenic PALB2 mutation in metastatic pancreatic adenocarcinoma and neuroendocrine tumour: A case report.

Authors:  David Chan; Stephen Clarke; Anthony J Gill; Lorraine Chantrill; Jas Samra; Bob T Li; Tristan Barnes; Kazi Nahar; Nick Pavlakis
Journal:  Mol Clin Oncol       Date:  2015-03-30

Review 3.  Pancreatic cancer: from state-of-the-art treatments to promising novel therapies.

Authors:  Ignacio Garrido-Laguna; Manuel Hidalgo
Journal:  Nat Rev Clin Oncol       Date:  2015-03-31       Impact factor: 66.675

4.  Whole genomes redefine the mutational landscape of pancreatic cancer.

Authors:  Nicola Waddell; Marina Pajic; Ann-Marie Patch; David K Chang; Karin S Kassahn; Peter Bailey; Amber L Johns; David Miller; Katia Nones; Kelly Quek; Michael C J Quinn; Alan J Robertson; Muhammad Z H Fadlullah; Tim J C Bruxner; Angelika N Christ; Ivon Harliwong; Senel Idrisoglu; Suzanne Manning; Craig Nourse; Ehsan Nourbakhsh; Shivangi Wani; Peter J Wilson; Emma Markham; Nicole Cloonan; Matthew J Anderson; J Lynn Fink; Oliver Holmes; Stephen H Kazakoff; Conrad Leonard; Felicity Newell; Barsha Poudel; Sarah Song; Darrin Taylor; Nick Waddell; Scott Wood; Qinying Xu; Jianmin Wu; Mark Pinese; Mark J Cowley; Hong C Lee; Marc D Jones; Adnan M Nagrial; Jeremy Humphris; Lorraine A Chantrill; Venessa Chin; Angela M Steinmann; Amanda Mawson; Emily S Humphrey; Emily K Colvin; Angela Chou; Christopher J Scarlett; Andreia V Pinho; Marc Giry-Laterriere; Ilse Rooman; Jaswinder S Samra; James G Kench; Jessica A Pettitt; Neil D Merrett; Christopher Toon; Krishna Epari; Nam Q Nguyen; Andrew Barbour; Nikolajs Zeps; Nigel B Jamieson; Janet S Graham; Simone P Niclou; Rolf Bjerkvig; Robert Grützmann; Daniela Aust; Ralph H Hruban; Anirban Maitra; Christine A Iacobuzio-Donahue; Christopher L Wolfgang; Richard A Morgan; Rita T Lawlor; Vincenzo Corbo; Claudio Bassi; Massimo Falconi; Giuseppe Zamboni; Giampaolo Tortora; Margaret A Tempero; Anthony J Gill; James R Eshleman; Christian Pilarsky; Aldo Scarpa; Elizabeth A Musgrove; John V Pearson; Andrew V Biankin; Sean M Grimmond
Journal:  Nature       Date:  2015-02-26       Impact factor: 49.962

5.  Hippo pathway mediates resistance to cytotoxic drugs.

Authors:  Taranjit S Gujral; Marc W Kirschner
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-17       Impact factor: 11.205

Review 6.  Translating cancer genomes and transcriptomes for precision oncology.

Authors:  Sameek Roychowdhury; Arul M Chinnaiyan
Journal:  CA Cancer J Clin       Date:  2015-11-03       Impact factor: 508.702

Review 7.  What can triumphs and tribulations from drug research in Alzheimer's disease tell us about the development of psychotropic drugs in general?

Authors:  Robert E Becker; Mary V Seeman; Nigel H Greig; Debomoy K Lahiri
Journal:  Lancet Psychiatry       Date:  2015-08       Impact factor: 27.083

Review 8.  Going to extremes: determinants of extraordinary response and survival in patients with cancer.

Authors:  Flurina A M Saner; Alan Herschtal; Brad H Nelson; Anna deFazio; Ellen L Goode; Susan J Ramus; Ahwan Pandey; Jessica A Beach; Sian Fereday; Andrew Berchuck; Stephanie Lheureux; Celeste Leigh Pearce; Paul D Pharoah; Malcolm C Pike; Dale W Garsed; David D L Bowtell
Journal:  Nat Rev Cancer       Date:  2019-06       Impact factor: 60.716

9.  Precision oncology in the age of integrative genomics.

Authors:  Chandan Kumar-Sinha; Arul M Chinnaiyan
Journal:  Nat Biotechnol       Date:  2018-01-10       Impact factor: 54.908

10.  Identification of a RAS-activating TMEM87A-RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non-Small Cell Lung Cancer.

Authors:  Alissa J Cooper; Yoshihisa Kobayashi; Dewey Kim; Sarah E Clifford; Sasha Kravets; Suzanne E Dahlberg; Emily S Chambers; Jiaqi Li; Deepa Rangachari; Tom Nguyen; Daniel B Costa; Michael S Rabin; Nikhil Wagle; Lynette M Sholl; Pasi A Jänne; Geoffrey R Oxnard
Journal:  Clin Cancer Res       Date:  2020-04-20       Impact factor: 12.531

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.