Literature DB >> 25687278

Biocatalysts for the formation of three- to six-membered carbo- and heterocycles.

Horst Lechner1, Desiree Pressnitz1, Wolfgang Kroutil2.   

Abstract

During the last decade, the number of different types of enzymes applicable for organic synthesis as biocatalysts has significantly increased. Consequently, the spectrum of reactions has significantly expanded also for cyclisations. This review highlights heterologously expressable biocatalysts transforming non-natural substrates for the formation of three- to six-membered carbo- and heterocycles, excluding terpene cyclases as well as SAM-dependent enzymes. The review focuses on the non-natural substrate scope and the mechanism of the selected enzymes.
Copyright © 2015. Published by Elsevier Inc.

Keywords:  Biocatalysis; Carbocycles; Cyclisation; Enzymes; Heterocycles; Non-natural substrates; Three–six membered rings

Mesh：

Substances：

Year:  2015        PMID： 25687278     DOI： 10.1016/j.biotechadv.2015.01.012

Source DB:  PubMed          Journal:  Biotechnol Adv        ISSN： 0734-9750            Impact factor:   14.227


  5 in total

Review 1.  Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides.

Authors:  Franziska Hemmerling; Frank Hahn
Journal:  Beilstein J Org Chem       Date:  2016-07-20       Impact factor: 2.883

Review 2.  Building Bridges: Biocatalytic C-C-Bond Formation toward Multifunctional Products.

Authors:  Nina G Schmidt; Elisabeth Eger; Wolfgang Kroutil
Journal:  ACS Catal       Date:  2016-06-08       Impact factor: 13.084

Review 3.  A Review: The Styrene Metabolizing Cascade of Side-Chain Oxygenation as Biotechnological Basis to Gain Various Valuable Compounds.

Authors:  Michel Oelschlägel; Juliane Zimmerling; Dirk Tischler
Journal:  Front Microbiol       Date:  2018-03-22       Impact factor: 5.640

4.  Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources.

Authors:  Shuke Wu; Yi Zhou; Daniel Gerngross; Markus Jeschek; Thomas R Ward
Journal:  Nat Commun       Date:  2019-11-07       Impact factor: 14.919

5.  Machine learning discovery of missing links that mediate alternative branches to plant alkaloids.

Authors:  Christopher J Vavricka; Shunsuke Takahashi; Naoki Watanabe; Musashi Takenaka; Mami Matsuda; Takanobu Yoshida; Ryo Suzuki; Hiromasa Kiyota; Jianyong Li; Hiromichi Minami; Jun Ishii; Kenji Tsuge; Michihiro Araki; Akihiko Kondo; Tomohisa Hasunuma
Journal:  Nat Commun       Date:  2022-03-16       Impact factor: 17.694
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.