| Literature DB >> 25683949 |
J Liu1.
Abstract
Irisin is a newly discovered 112 amino acid residues' glycosylated protein hormone that was firstly found up-regulated by exercise-induced peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) and then play an important role in circulation so as to target other organs. It conducts many downstream events including osteoblast differentiation, nerve cell and β-cell regeneration and so on. In clinical research, non-inflammation and inflammation related diseases correlated with basal level of irisin and they benefited from exercise-induced irisin endocrinology.Entities:
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Year: 2015 PMID: 25683949
Source DB: PubMed Journal: Eur Rev Med Pharmacol Sci ISSN: 1128-3602 Impact factor: 3.507