Literature DB >> 25683611

FOXP3+ regulatory T cells and their functional regulation.

Zhiyuan Li1, Dan Li1, Andy Tsun1,2, Bin Li1.   

Abstract

FOXP3(+) regulatory T (Treg) cells are critical in maintaining immune tolerance and homeostasis of the immune system. The molecular mechanisms underlying the stability, plasticity and functional activity of Treg cells have been much studied in recent years. Here, we summarize these intriguing findings, and provide insight into their potential use or manipulation during Treg cell therapy for the treatment of autoimmune diseases, graft-versus-host disease (GVHD) and cancer.

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Year:  2015        PMID： 25683611      PMCID： PMC4579651          DOI： 10.1038/cmi.2015.10

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  89 in total

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Authors:  G Manning; D B Whyte; R Martinez; T Hunter; S Sudarsanam
Journal:  Science       Date:  2002-12-06       Impact factor: 47.728

2.  Control of regulatory T cell development by the transcription factor Foxp3.

Authors:  Shohei Hori; Takashi Nomura; Shimon Sakaguchi
Journal:  Science       Date:  2003-01-09       Impact factor: 47.728

3.  Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.

Authors:  Jason D Fontenot; Marc A Gavin; Alexander Y Rudensky
Journal:  Nat Immunol       Date:  2003-03-03       Impact factor: 25.606

4.  An essential role for Scurfin in CD4+CD25+ T regulatory cells.

Authors:  Roli Khattri; Tom Cox; Sue-Ann Yasayko; Fred Ramsdell
Journal:  Nat Immunol       Date:  2003-03-03       Impact factor: 25.606

5.  Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions.

Authors:  Ling Lu; Qin Lan; Zhiyuan Li; Xiaohui Zhou; Jian Gu; Qiang Li; Julie Wang; Maogen Chen; Ya Liu; Yi Shen; David D Brand; Bernhard Ryffel; David A Horwitz; Francisco P Quismorio; Zhongmin Liu; Bin Li; Nancy J Olsen; Song Guo Zheng
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-06       Impact factor: 11.205

6.  TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2.

Authors:  Chihiro Ogawa; Yukiko Tone; Masato Tsuda; Christian Peter; Herman Waldmann; Masahide Tone
Journal:  J Immunol       Date:  2013-12-02       Impact factor: 5.422

7.  Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

Authors:  Noriko Komatsu; Kazuo Okamoto; Shinichiro Sawa; Tomoki Nakashima; Masatsugu Oh-hora; Tatsuhiko Kodama; Sakae Tanaka; Jeffrey A Bluestone; Hiroshi Takayanagi
Journal:  Nat Med       Date:  2013-12-22       Impact factor: 53.440

8.  CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes.

Authors:  E Allison Green; Leonid Gorelik; Catrin M McGregor; Elise H Tran; Richard A Flavell
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-29       Impact factor: 11.205

9.  Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide.

Authors:  Christopher G Kanakry; Sudipto Ganguly; Marianna Zahurak; Javier Bolaños-Meade; Christopher Thoburn; Brandy Perkins; Ephraim J Fuchs; Richard J Jones; Allan D Hess; Leo Luznik
Journal:  Sci Transl Med       Date:  2013-11-13       Impact factor: 17.956

10.  Phosphorylation of FOXP3 by LCK downregulates MMP9 expression and represses cell invasion.

Authors:  Kumiko Nakahira; Akihiro Morita; Nam-Soon Kim; Itaru Yanagihara
Journal:  PLoS One       Date:  2013-10-14       Impact factor: 3.240
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  85 in total

1.  How regulatory T cells sense and adapt to inflammation.

Authors:  Bin Li; Song Guo Zheng
Journal:  Cell Mol Immunol       Date:  2015-08-17       Impact factor: 11.530

Review 2.  The endometrial immune environment of women with endometriosis.

Authors:  Júlia Vallvé-Juanico; Sahar Houshdaran; Linda C Giudice
Journal:  Hum Reprod Update       Date:  2019-09-11       Impact factor: 15.610

3.  ImmTAC/Anti-PD-1 antibody combination to enhance killing of cancer cells by reversing regulatory T-cell-mediated immunosuppression.

Authors:  Huanling Zhang; Yanyan Li; Xiaoping Liu; Zhaoduan Liang; Mengyong Yan; Qiang Liu; Anan Chen; Yifeng Bao; Chengzhi Zhou; Shiyue Li; Cassian Yee; Yi Li
Journal:  Immunology       Date:  2018-06-14       Impact factor: 7.397

4.  Frequently Increased but Functionally Impaired CD4+CD25+ Regulatory T Cells in Patients with Oral Lichen Planus.

Authors:  Leilei Zhou; Tianyi Cao; Yufeng Wang; Hui Yao; Guanhuan Du; Guangjie Chen; Xiaoyin Niu; Guoyao Tang
Journal:  Inflammation       Date:  2016-06       Impact factor: 4.092

Review 5.  Regulatory T cells in skin.

Authors:  Niwa Ali; Michael D Rosenblum
Journal:  Immunology       Date:  2017-08-04       Impact factor: 7.397

6.  Impaired regulatory T cell function in autoimmune diseases: are microRNAs the culprits?

Authors:  Varun K Sharma; Srini V Kaveri; Jagadeesh Bayry
Journal:  Cell Mol Immunol       Date:  2015-12-14       Impact factor: 11.530

7.  The frequency and skewed T-cell receptor beta-chain variable patterns of peripheral CD4(+)CD25(+) regulatory T-cells are associated with hepatitis B e antigen seroconversion of chronic hepatitis B patients during antiviral treatment.

Authors:  Jiezuan Yang; Guoping Sheng; Dangsheng Xiao; Haiyan Shi; Wei Wu; Haifeng Lu; Hongcui Cao; Lanjuan Li
Journal:  Cell Mol Immunol       Date:  2016-02-22       Impact factor: 11.530

Review 8.  Challenges and future perspectives of T cell immunotherapy in cancer.

Authors:  Maria Teresa P de Aquino; Anshu Malhotra; Manoj K Mishra; Anil Shanker
Journal:  Immunol Lett       Date:  2015-06-19       Impact factor: 3.685

9.  Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.

Authors:  Megan M Blewett; Jiji Xie; Balyn W Zaro; Keriann M Backus; Amnon Altman; John R Teijaro; Benjamin F Cravatt
Journal:  Sci Signal       Date:  2016-09-13       Impact factor: 8.192

10.  Effects of Shen-Fu Injection () on apoptosis of regulatory T lymphocytes in spleen during post-resuscitation immune dysfunction in a porcine model of cardiac arrest.

Authors:  Wei Gu; Qian Zhang; Chun-Sheng Li
Journal:  Chin J Integr Med       Date:  2016-09-11       Impact factor: 1.978
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