Jong Man Kim1, Bong Ick Cho1, Choon Hyuck David Kwon1, Jae-Won Joh2, Jae Berm Park1, Joon Hyeok Lee3, Sung Joo Kim1, Seung Woon Paik3, Cheol Keun Park4. 1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong Gangnam-Gu, Seoul 135-710, Korea. 2. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong Gangnam-Gu, Seoul 135-710, Korea. Electronic address: jw.joh@samsung.com. 3. Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 4. Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Abstract
BACKGROUND: Hepatic resection is the main treatment for patients with hepatocellular carcinoma. However, surgery is generally stressful for older patients. METHODS: Clinicopathologic data and outcomes after hepatic resection were retrospectively investigated for older patients with hepatocellular carcinoma. The younger group (n = 219) included patients aged 60 to 69 years, and the older group (n = 60) included patients >70 years of age. RESULTS: Hepatitis B virus was more common in the younger group than in the older group (64.5% vs 28.8%, P < .001). The occurrence of pneumonia was higher in older group than in the younger group (10.0% vs 2.3%, P = .015), but postoperative complications and mortality were not significantly different between the 2 groups. There was no statistically significant difference in disease-free survival rates between the 2 groups. CONCLUSIONS: Although the incidence of postoperative pneumonia was higher in the older group than in the younger group, hepatic resection was justified for hepatocellular carcinoma in selected patients >70 years of age. Crown
BACKGROUND: Hepatic resection is the main treatment for patients with hepatocellular carcinoma. However, surgery is generally stressful for older patients. METHODS: Clinicopathologic data and outcomes after hepatic resection were retrospectively investigated for older patients with hepatocellular carcinoma. The younger group (n = 219) included patients aged 60 to 69 years, and the older group (n = 60) included patients >70 years of age. RESULTS:Hepatitis B virus was more common in the younger group than in the older group (64.5% vs 28.8%, P < .001). The occurrence of pneumonia was higher in older group than in the younger group (10.0% vs 2.3%, P = .015), but postoperative complications and mortality were not significantly different between the 2 groups. There was no statistically significant difference in disease-free survival rates between the 2 groups. CONCLUSIONS: Although the incidence of postoperative pneumonia was higher in the older group than in the younger group, hepatic resection was justified for hepatocellular carcinoma in selected patients >70 years of age. Crown
Authors: Amir A Rahnemai-Azar; Jordan M Cloyd; Sharon M Weber; Mary Dillhoff; Carl Schmidt; Emily R Winslow; Timothy M Pawlik Journal: J Clin Transl Hepatol Date: 2017-11-30
Authors: Jong Man Kim; Jinsoo Rhu; Sang Yun Ha; Gyu-Seong Choi; Choon Hyuck David Kwon; Gaabsoo Kim; Jae-Won Joh Journal: Ann Surg Treat Res Date: 2021-10-29 Impact factor: 1.859