Literature DB >> 25681217

Acute appendicitis in the elderly in the twenty-first century.

Lior Segev1, Andrei Keidar, Ilan Schrier, Shlomi Rayman, Nir Wasserberg, Eran Sadot.   

Abstract

BACKGROUND: The incidence of appendicitis in the elderly has risen. Older age is an independent predictor of poor surgical outcome. Herein, we present the most comprehensive single institution study to describe the natural history and outcome of appendicitis in elderly patients.
METHODS: A review of 1898 consecutive patients who underwent appendectomy between 2004 and 2007 was performed. The elderly patients were defined as older than 68 years.
RESULTS: The median age of the entire cohort was 25 years, and 55% were males. The elderly group included 68 patients (3.6%). On comparison by age, the elderly group had a significantly longer delay from symptom onset to admission (50 vs. 31 h, P = 0.01) and from admission to surgery, a longer operative time and hospital stay, and higher rates of postoperative complications and complicated appendicitis.
CONCLUSION: The current study demonstrated several unique characteristics of the elderly population with acute appendicitis, which include poor outcome and longer time intervals to diagnosis and treatment. In order to improve the poor outcome of the elderly population with appendicitis, prospective trials are necessary.

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Year:  2015        PMID: 25681217     DOI: 10.1007/s11605-014-2716-9

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  30 in total

Review 1.  Use of antibiotics alone for treatment of uncomplicated acute appendicitis: a systematic review and meta-analysis.

Authors:  Katherine Liu; Louis Fogg
Journal:  Surgery       Date:  2011-10       Impact factor: 3.982

2.  Laparoscopic appendectomy is safe and efficacious for the elderly: an analysis using the National Surgical Quality Improvement Project database.

Authors:  Michael J Kim; Fergal J Fleming; Douglas D Gunzler; Susan Messing; Rabih M Salloum; John R T Monson
Journal:  Surg Endosc       Date:  2011-02-07       Impact factor: 4.584

3.  Appendectomy versus antibiotic treatment in acute appendicitis. a prospective multicenter randomized controlled trial.

Authors:  Johan Styrud; Staffan Eriksson; Ingemar Nilsson; Gunnar Ahlberg; Staffan Haapaniemi; Gunnar Neovius; Lars Rex; Ibrahim Badume; Lars Granström
Journal:  World J Surg       Date:  2006-06       Impact factor: 3.352

4.  Antibiotic therapy for appendicitis in patients aged ≥80 years.

Authors:  Hyoung-Chul Park; Min Jeong Kim; Bong Hwa Lee
Journal:  Am J Med       Date:  2014-02-03       Impact factor: 4.965

5.  What have we learned over the past 20 years about appendicitis in the elderly?

Authors:  Toni L Storm-Dickerson; Mark C Horattas
Journal:  Am J Surg       Date:  2003-03       Impact factor: 2.565

6.  Increased morbidity of appendicitis with advancing age.

Authors:  M G Franz; J Norman; P J Fabri
Journal:  Am Surg       Date:  1995-01       Impact factor: 0.688

7.  Perforated appendicitis: is it truly a surgical urgency?

Authors:  D Yamini; H Vargas; F Bongard; S Klein; M J Stamos
Journal:  Am Surg       Date:  1998-10       Impact factor: 0.688

8.  Acute appendicitis in the elderly.

Authors:  W Y Lau; S T Fan; T F Yiu; K W Chu; J M Lee
Journal:  Surg Gynecol Obstet       Date:  1985-08

9.  Identification of specific quality improvement opportunities for the elderly undergoing gastrointestinal surgery.

Authors:  David J Bentrem; Mark E Cohen; Denise M Hynes; Clifford Y Ko; Karl Y Bilimoria
Journal:  Arch Surg       Date:  2009-11

Review 10.  Surgical considerations in older adults with cancer.

Authors:  Beatriz Korc-Grodzicki; Robert J Downey; Armin Shahrokni; T Peter Kingham; Snehal G Patel; Riccardo A Audisio
Journal:  J Clin Oncol       Date:  2014-07-28       Impact factor: 44.544

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  11 in total

1.  Acute Appendicitis During Pregnancy: Different from the Nonpregnant State?

Authors:  L Segev; Y Segev; S Rayman; A Nissan; E Sadot
Journal:  World J Surg       Date:  2017-01       Impact factor: 3.352

2.  The clinical impact of frailty on the postoperative outcomes of patients undergoing appendectomy: propensity score-matched analysis of 2011-2017 US hospitals.

Authors:  David Uihwan Lee; David Jeffrey Hastie; Ki Jung Lee; Gregory Hongyuan Fan; Elyse Ann Addonizio; John Han; Julie Suh; Raffi Karagozian
Journal:  Aging Clin Exp Res       Date:  2022-06-20       Impact factor: 4.481

3.  Clinical-pathological features and treatment of acute appendicitis in the very elderly: an interim analysis of the FRAILESEL Italian multicentre prospective study.

Authors:  Pietro Fransvea; Valeria Fico; Valerio Cozza; Gianluca Costa; Luca Lepre; Paolo Mercantini; Antonio La Greca; Gabriele Sganga
Journal:  Eur J Trauma Emerg Surg       Date:  2021-03-18       Impact factor: 3.693

4.  Comparison of Clinical Features and Outcomes of Appendectomy in Elderly vs. Non-Elderly: A Systematic Review and Meta-Analysis.

Authors:  Jie Yuan; Qingfeng Chen; Weicong Hong; Lifeng Yu; Xuen Li
Journal:  Front Surg       Date:  2022-02-21

5.  The treatment of acute appendicitis in two age-based groups during COVID-19 pandemic: a retrospective experience in a COVID-19 referral hospital.

Authors:  Giorgio Lisi; Michela Campanelli; Maria Rosaria Mastrangeli; Domenico Spoletini; Rosa Menditto; Simona Grande; Massimiliano Boccuzzi; Michele Grande
Journal:  Int J Colorectal Dis       Date:  2021-11-04       Impact factor: 2.571

6.  Preoperative neutrophil-to-lymphocyte ratio may contribute to the prediction of postoperative infectious complications in patients with acute appendicitis: a retrospective study.

Authors:  Mikito Mori; Kazuo Narushima; Atsushi Hirano; Yoshihiko Kano; Fumihiro Chiba; Yoshihiro Edamoto; Masahiro Yoshida
Journal:  BMC Surg       Date:  2022-03-03       Impact factor: 2.102

7.  Acute appendicitis in elderly during Covid-19 pandemic.

Authors:  G Lisi; M Campanelli; M R Mastrangeli; S Grande; M A Viarengo; G M Garbarino; G Vanni; M Grande
Journal:  Int J Colorectal Dis       Date:  2021-05-27       Impact factor: 2.796

Review 8.  Emergency surgery in the elderly: challenges and solutions.

Authors:  Andrew D W Torrance; Susan L Powell; Ewen A Griffiths
Journal:  Open Access Emerg Med       Date:  2015-09-08

9.  Prediction of Negative Outcomes in Non-Surgical Treatment for Appendiceal Abscess in Adults.

Authors:  Yoshihiko Sadakari; Satomi Date; Soichiro Murakami; Shu Ichimiya; Shiho Nishimura; Hitomi Kawaji; Akiko Sagara; Jaymel R Castillo; Mikimasa Ishikawa; Tetsuro Kamimura; Akihiko Uchiyama; Masafumi Nakamura
Journal:  J Anus Rectum Colon       Date:  2018-04-26

Review 10.  The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition).

Authors:  Paola Fugazzola; Marco Ceresoli; Vanni Agnoletti; Ferdinando Agresta; Bruno Amato; Paolo Carcoforo; Fausto Catena; Osvaldo Chiara; Massimo Chiarugi; Lorenzo Cobianchi; Federico Coccolini; Alessandro De Troia; Salomone Di Saverio; Andrea Fabbri; Carlo Feo; Francesco Gabrielli; Angela Gurrado; Angelo Guttadauro; Leonardo Leone; Daniele Marrelli; Luca Petruzzelli; Nazario Portolani; Francesco Paolo Prete; Alessandro Puzziello; Massimo Sartelli; Giorgio Soliani; Mario Testini; Salvatore Tolone; Matteo Tomasoni; Gregorio Tugnoli; Pierluigi Viale; Monica Zese; Offir Ben Ishay; Yoram Kluger; Andrew Kirkpatrick; Luca Ansaloni
Journal:  World J Emerg Surg       Date:  2020-03-10       Impact factor: 5.469

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