Literature DB >> 25681114

[Neurosurgical treatment of chronic pain].

D Fontaine1, S Blond2, P Mertens3, M Lanteri-Minet4.   

Abstract

Neurosurgical treatment of pain used two kind of techniques: 1) Lesional techniques interrupt the transmission of nociceptive neural input by lesionning the nociceptive pathways (drezotomy, cordotomy, tractotomy…). They are indicated to treat morphine-resistant cancer pain and few cases of selected neuropathic pain. 2) Neuromodulation techniques try to decrease pain by reinforcing inhibitory and/or to limit activatory mechanisms. Chronic electrical stimulation of the nervous system (peripheral nerve stimulation, spinal cord stimulation, motor cortex stimulation…) is used to treat chronic neuropathic pain. Intrathecal infusion of analgesics (morphine, ziconotide…), using implantable pumps, allows to increase their efficacy and to reduce their side effects. These techniques can improve, sometimes dramatically, selected patients with severe and chronic pain, refractory to all other treatments. The quality of the analgesic outcome depends on the relevance of the indications.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Chirurgie; Chronic pain; Douleur chronique; Drezotomie; Drezotomy; Intrathecal therapy; Motor cortex stimulation; Neuromodulation; Spinal cord stimulation; Stimulation corticale; Stimulation médullaire; Surgery; Thérapie intrathécale

Mesh:

Substances:

Year:  2015        PMID: 25681114     DOI: 10.1016/j.neuchi.2014.11.008

Source DB:  PubMed          Journal:  Neurochirurgie        ISSN: 0028-3770            Impact factor:   1.553


  3 in total

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Authors:  Xiaolin Pang; Yuanzhang Tang; Dongya Zhang
Journal:  Exp Ther Med       Date:  2016-11-14       Impact factor: 2.447

2.  Stress-related hormone reduces autophagy through the regulation of phosphatidylethanolamine in breast cancer cells.

Authors:  Zhen Zhu; Ruihua Yu; Chao Yang; Dong Li; Jiawei Wang; Wanli Yang; Yonghua Ji; Li Wang; Yaosheng Wang; Feng Jiang
Journal:  Ann Transl Med       Date:  2021-01

3.  Development and Validation of a Predictive Model of Pain Modulation Profile to Guide Chronic Pain Treatment: A Study Protocol.

Authors:  Matthieu Vincenot; Alexia Coulombe-Lévêque; Monica Sean; Félix Camirand Lemyre; Louis Gendron; Serge Marchand; Guillaume Léonard
Journal:  Front Pain Res (Lausanne)       Date:  2021-02-15
  3 in total

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