Literature DB >> 25680474

Intravenous acetaminophen in bariatric surgery: effects on opioid requirements.

Anthony Michael Gonzalez1, Rey Jesús Romero2, Maria M Ojeda-Vaz3, Jorge Rafael Rabaza2.   

Abstract

BACKGROUND: Opioids are commonly used after bariatric surgery for pain control because of their potent analgesic effects. Nevertheless, the morbidly obese patient has increased risk for developing adverse effects produced by opioids (such as sedation, apnea, hypoxemia, ileus, and vomiting). Intravenous acetaminophen (IVA) has been evaluated in some specialties showing a reduction in opioid consumption. The purpose of this study was to evaluate the effect on opioid consumption when IVA is administered in bariatric surgery patients.
MATERIAL AND METHODS: A retrospective study was performed in patients who underwent bariatric surgery. Group A included those patients who received IVA perioperatively and group B those who did not. The amount of opioids administered was calculated and compared for each group.
RESULTS: Group A included 38 cases (44.7%) and group B included 47 cases (55.3%). A comparison was performed in terms of age (P = 0.349), body mass index (P = 0.311), gender (P = 0.890), American Society of Anesthesiologist score (P = 0.438), total surgical time (P = 0.497), perioperative complications (P = 0.786), number of procedures per surgeon (P = 0.08), and type of surgical procedure (P ≤ 0.01). Group A had a mean 24-h total opioid dose of 99.5 mg, whereas group B of 164.6 mg (P = 0.018). Group A received 39.5% less opioids than group B. A post hoc analysis determined a statistical power of 0.74.
CONCLUSIONS: IVA used perioperatively can decrease opioid consumption in patients after bariatric surgery. Randomized trials are needed to corroborate these results.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Bariatric surgery; IV acetaminophen; Ofirmev; Opioids; Pain

Mesh:

Substances:

Year:  2015        PMID: 25680474     DOI: 10.1016/j.jss.2015.01.004

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  6 in total

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Authors:  Kangwon Song; Isaac Samuel; Patrick Ziemann-Gimmel
Journal:  P T       Date:  2016-06

2.  Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.

Authors:  Bahadır Ciftci; Mursel Ekinci; Erkan Cem Celik; Ahmet Kaciroglu; Muhammet Ahmet Karakaya; Yavuz Demiraran; Yasar Ozdenkaya
Journal:  Obes Surg       Date:  2019-03       Impact factor: 4.129

3.  Perioperative Analgesia for Fast-Track Laparoscopic Bariatric Surgery.

Authors:  Olumuyiwa A Bamgbade; Oluwafemi Oluwole; Rong R Khaw
Journal:  Obes Surg       Date:  2017-07       Impact factor: 4.129

4.  The Effect of Scheduled Intravenous Acetaminophen in an Enhanced Recovery Protocol Pathway in Patients Undergoing Major Abdominal Procedures: A Prospective, Randomized, and Placebo-Controlled Clinical Trial.

Authors:  Kathirvel Subramaniam; Stephen A Esper; Kushanth Mallikarjun; Alec Dickson; Kristin Ruppert DrPH; Tomas Drabek; Hesper Wong; Jennifer Holder-Murray
Journal:  Pain Med       Date:  2022-01-03       Impact factor: 3.637

5.  Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Authors:  Hamed Elgendy; Talha Youssef; Ahmad Banjar; Soha Elmorsy
Journal:  Obes Surg       Date:  2020-07       Impact factor: 4.129

6.  Efficacy of Intravenous Acetaminophen in Length of Stay and Postoperative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery Patients.

Authors:  Matthew Lange; Christina W Lee; Tara Knisely; Subbaiah Perla; Kimberly Barber; Michael Kia
Journal:  Bariatr Surg Pract Patient Care       Date:  2018-09-01       Impact factor: 0.607

  6 in total

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