Literature DB >> 25680099

Nanocarriers in therapy of infectious and inflammatory diseases.

Ufuoma Ikoba1, Haisheng Peng, Haichun Li, Cathy Miller, Chenxu Yu, Qun Wang.   

Abstract

Nanotechnology is a growing science that has applications in various areas of medicine. The composition of nanocarriers for drug delivery is critical to guarantee high therapeutic performance when targeting specific host sites. Applications of nanotechnology are prevalent in the diagnosis and treatment of infectious and inflammatory diseases. This review summarizes recent advancements in the application of nanotechnology to the therapy of infectious and inflammatory diseases. The major focus is on the design and fabrication of various nanomaterials, characteristics and physicochemical properties of drug-loaded nanocarriers, and the use of these nanoscale drug delivery systems in treating infectious and inflammatory diseases, such as AIDS, hepatitis, tuberculosis, melanoma, and representative inflammatory diseases. Clinical trials and future perspective of the use of nanocarriers are also discussed in detail. We hope that such a review will be valuable to researchers who are exploring nanoscale drug delivery systems for the treatment of specific infectious and inflammatory diseases.

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Year:  2015        PMID: 25680099     DOI: 10.1039/c4nr07682f

Source DB:  PubMed          Journal:  Nanoscale        ISSN: 2040-3364            Impact factor:   7.790


  15 in total

1.  Encapsulation of Anticancer Drugs (5-Fluorouracil and Paclitaxel) into Polycaprolactone (PCL) Nanofibers and In Vitro Testing for Sustained and Targeted Therapy.

Authors:  Sakib Iqbal; Mohammad H Rashid; Ali S Arbab; Mujibur Khan
Journal:  J Biomed Nanotechnol       Date:  2017-04       Impact factor: 4.099

2.  Microparticulate/Nanoparticulate Powders of a Novel Nrf2 Activator and an Aerosol Performance Enhancer for Pulmonary Delivery Targeting the Lung Nrf2/Keap-1 Pathway.

Authors:  Priya Muralidharan; Don Hayes; Stephen M Black; Heidi M Mansour
Journal:  Mol Syst Des Eng       Date:  2016-01-27

3.  Enhanced cellular osteogenic differentiation on Zn-containing bioglass incorporated TiO2 nanorod films.

Authors:  Meng He; Xiaoyi Chen; Kui Cheng; Lingqing Dong; Wenjian Weng; Huiming Wang
Journal:  J Mater Sci Mater Med       Date:  2018-08-17       Impact factor: 3.896

Review 4.  Biomedical nanomaterials for immunological applications: ongoing research and clinical trials.

Authors:  Vincent Lenders; Xanthippi Koutsoumpou; Ara Sargsian; Bella B Manshian
Journal:  Nanoscale Adv       Date:  2020-08-24

5.  Destruction of Opportunistic Pathogens via Polymer Nanoparticle-Mediated Release of Plant-Based Antimicrobial Payloads.

Authors:  Dahlia N Amato; Douglas V Amato; Olga V Mavrodi; Dwaine A Braasch; Susan E Walley; Jessica R Douglas; Dmitri V Mavrodi; Derek L Patton
Journal:  Adv Healthc Mater       Date:  2016-03-04       Impact factor: 9.933

6.  Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA.

Authors:  Bin Li; Xiao Luo; Binbin Deng; JoLynn B Giancola; David W McComb; Thomas D Schmittgen; Yizhou Dong
Journal:  Sci Rep       Date:  2016-02-26       Impact factor: 4.379

7.  Nanoparticle Delivery of Artesunate Enhances the Anti-tumor Efficiency by Activating Mitochondria-Mediated Cell Apoptosis.

Authors:  Rui Liu; Xiwei Yu; Chang Su; Yijie Shi; Liang Zhao
Journal:  Nanoscale Res Lett       Date:  2017-06-12       Impact factor: 4.703

8.  Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients.

Authors:  Hyung-Jun Im; Kwon Joong Na; Hongyoon Choi; Hyunjong Lee; Jeongbin Park
Journal:  Sci Rep       Date:  2021-07-08       Impact factor: 4.379

9.  Therapeutic Potential of Delivering Arsenic Trioxide into HPV-Infected Cervical Cancer Cells Using Liposomal Nanotechnology.

Authors:  Xiaoyan Wang; Dong Li; Lucy Ghali; Ruidong Xia; Leonardo P Munoz; Hemda Garelick; Celia Bell; Xuesong Wen
Journal:  Nanoscale Res Lett       Date:  2016-02-18       Impact factor: 4.703

10.  Intracellular targeted co-delivery of shMDR1 and gefitinib with chitosan nanoparticles for overcoming multidrug resistance.

Authors:  Xiwei Yu; Guang Yang; Yijie Shi; Chang Su; Ming Liu; Bo Feng; Liang Zhao
Journal:  Int J Nanomedicine       Date:  2015-11-12
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