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Literature DB >> 25680085

Real time detection of live microbes using a highly sensitive bioluminescent nitroreductase probe.

Roger H F Wong¹, Thomas Kwong, Kwok-Hei Yau, Ho Yu Au-Yeung.

Abstract

A highly sensitive and selective nitroreductase probe, showing a rapid and strong bioluminescence enhancement (>100-fold in 5 minutes), and its initial application in the real time detection of both Gram positive and Gram negative live bacteria and monitoring of their growth has been reported.

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Year: 2015 PMID： 25680085 DOI： 10.1039/c4cc10345a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

8 in total

1. In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation.

Authors: Jian Cao; James Campbell; Li Liu; Ralph P Mason; Alexander R Lippert
Journal: Anal Chem Date: 2016-04-15 Impact factor: 6.986

Review 2. Recent progress in the imaging detection of enzyme activities in vivo.

Authors: Chunjie Yang; Qian Wang; Wu Ding
Journal: RSC Adv Date: 2019-08-13 Impact factor: 4.036

3. Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[¹⁸F]F-p-Aminobenzoic Acid.

Authors: Yong Li; Fereidoon Daryaee; Grace E Yoon; Doyoung Noh; Peter M Smith-Jones; Yuanyuan Si; Stephen G Walker; Nashaat Turkman; Labros Meimetis; Peter J Tonge
Journal: ACS Infect Dis Date: 2020-07-31 Impact factor: 5.084

4. A General Approach to Convert Hemicyanine Dyes into Highly Optimized Photoacoustic Scaffolds for Analyte Sensing*.

Authors: Sarah H Gardner; Catharine J Brady; Cameron Keeton; Anuj K Yadav; Sharath C Mallojjala; Melissa Y Lucero; Shengzhang Su; Zhengxin Yu; Jennifer S Hirschi; Liviu M Mirica; Jefferson Chan
Journal: Angew Chem Int Ed Engl Date: 2021-07-01 Impact factor: 16.823

Real time detection of live microbes using a highly sensitive bioluminescent nitroreductase probe.

1. In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation.

Review 2. Recent progress in the imaging detection of enzyme activities in vivo.

3. Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[¹⁸F]F-p-Aminobenzoic Acid.

4. A General Approach to Convert Hemicyanine Dyes into Highly Optimized Photoacoustic Scaffolds for Analyte Sensing*.

5. Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe.

6. A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging.

7. Novel caged luciferin derivatives can prolong bioluminescence imaging in vitro and in vivo.

8. An Activatable Lanthanide Luminescent Probe for Time-Gated Detection of Nitroreductase in Live Bacteria.