Fatemeh Nayeri1, Firozeh Nili2, Bita Ebrahim3, Zohreh Olomie Yazdi4, Zahra Maliki5. 1. 1. Neonatologist, Family Health Institute, Maternal- Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran. fnayeri@tums.ac.ir. 2. 2. Neonatologist, Family Health Institute, Maternal- Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran. fnili@sina.tums.ac.ir. 3. 3. Pediatrician, Family Health Institute, Breast Feeding Research Center, Tehran University of Medical Sciences, Tehran, Iran. BitaEbrahim@yahoo.ca. 4. 4. Pediatrician, Oncologist, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran. mfnhrc@tums.ac.ir. 5. 5. Pediatrician, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran. mfnhrc@yahoo.com.
Abstract
BACKGROUND: Although transfusion is a common procedure for treating anemia of prematurity, there is no specific protocol for blood transfusion in premature newborns. So in this study we investigate whether application of a strict protocol has any statistically significant effect on reduction of blood transfusion. METHODS: In this study, first group admitted in NICU during 2005 - 2006 and the second group admitted during 2006 - 2007. Whereas in the first group the blood transfusion performed based on neonatologists' opinion following consultations with a pediatric hematologist, blood transfusion in the second group was based on the Shannon's protocol. RESULTS: During 2005-2006, out of 206 cases, 71 cases (%34.5) underwent blood infusion. During 2006-2007, out of 211 cases, 56 (%26.5) received blood transfusion based on the Shannon's strict protocol. Although the number of cases decreased, no significant difference was found betweenthe two groups (p= 0.07). Conculsion: Applying strict criteria alone is not effective in reducing the frequency of transfusion in infants.
BACKGROUND: Although transfusion is a common procedure for treating anemia of prematurity, there is no specific protocol for blood transfusion in premature newborns. So in this study we investigate whether application of a strict protocol has any statistically significant effect on reduction of blood transfusion. METHODS: In this study, first group admitted in NICU during 2005 - 2006 and the second group admitted during 2006 - 2007. Whereas in the first group the blood transfusion performed based on neonatologists' opinion following consultations with a pediatric hematologist, blood transfusion in the second group was based on the Shannon's protocol. RESULTS: During 2005-2006, out of 206 cases, 71 cases (%34.5) underwent blood infusion. During 2006-2007, out of 211 cases, 56 (%26.5) received blood transfusion based on the Shannon's strict protocol. Although the number of cases decreased, no significant difference was found betweenthe two groups (p= 0.07). Conculsion: Applying strict criteria alone is not effective in reducing the frequency of transfusion in infants.
Authors: A M Miyashiro; N dos Santos; R Guinsburg; B I Kopelman; C de Araújo Peres; M F de Lima Taga; A R Shinzato; H de Paula Fiod Costa Journal: Vox Sang Date: 2005-02 Impact factor: 2.144