Gilda Cennamo1, Elisabetta Chiariello Vecchio2, Marialuisa Finelli2, Nunzio Velotti2, Giuseppe de Crecchio2. 1. Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy. Electronic address: xgilda@hotmail.com. 2. Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
Abstract
OBJECTIVE: To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy. DESIGN: Prospective noninterventional study. PARTICIPANTS: Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study. METHODS: Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated. RESULTS: GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity (R=0.783, R(2)=0.611). CONCLUSIONS: GCC thickness and microperimetry integrated with fluorescein angiography could be a marker of retinal vascular abnormalities that is useful for the diagnosis of ischemic diabetic maculopathy.
OBJECTIVE: To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy. DESIGN: Prospective noninterventional study. PARTICIPANTS: Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study. METHODS: Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated. RESULTS: GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity (R=0.783, R(2)=0.611). CONCLUSIONS: GCC thickness and microperimetry integrated with fluorescein angiography could be a marker of retinal vascular abnormalities that is useful for the diagnosis of ischemic diabetic maculopathy.
Authors: Emily S Levine; Eric M Moult; Eugenia Custo Greig; Yi Zhao; Varsha Pramil; Isaac Gendelman; Agha Y Alibhai; Caroline R Baumal; Andre J Witkin; Jay S Duker; James G Fujimoto; Nadia K Waheed Journal: Retina Date: 2022-02-01 Impact factor: 4.256