Khalil Ghasemi Falavarjani1, Mohammadreza Aghamirsalim2, Mehdi Modarres3, Ali Hadavandkhani2, Masih Hashemi3, Mohammad Mehdi Parvaresh3, Masood Naseripour3, Nasrollah Samiy4. 1. Department of Ophthalmology, Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences. Electronic address: drghasemi@yahoo.com. 2. Department of Ophthalmology, Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences. 3. Department of Ophthalmology, Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences; Markazi Eye Clinic, Tehran, Iran. 4. Retina Institute of the Carolinas, Charlotte, N.C.
Abstract
OBJECTIVE: To evaluate the rate of acute endophthalmitis after resident-performed intravitreal bevacizumab (IVB) injections and to compare the results with those performed by attending retina surgeons. DESIGN: Retrospective comparative case series. PARTICIPANTS: Eight thousand thirty-seven patients treated with intravitreal injection of bevacizumab. METHODS: A retrospective chart review of the resident-performed IVB injections at Rassoul Akram Hospital and attending-performed IVB injections at a private eye clinic between 2011 and 2014 was undertaken. Cases of clinical endophthalmitis were identified. RESULTS: During the study interval, the overall incidence rate of postinjection endophthalmitis was 0.01% (1/8037). Antibiotic eye drops were prescribed after IVB injection for 2771 eyes (34.5%). The single case of acute endophthalmitis occurred after a resident-performed injection, and vitreous culture showed growth of Staphylococcus epidermidis. The incidence rate of acute endophthalmitis after resident-performed IVB injection was 0.02% (1/4921). No statistically significant difference was found in the rates of endophthalmitis between resident-performed and attending-performed injections (p = 1). Also, the difference in the rates of endophthalmitis between those receiving postinjection antibiotics and those who did not was not statistically significant (p = 0.3). CONCLUSIONS: The risk for endophthalmitis after resident-performed IVB injection is low and similar to that of the supervising surgeons performing the procedure.
OBJECTIVE: To evaluate the rate of acute endophthalmitis after resident-performed intravitreal bevacizumab (IVB) injections and to compare the results with those performed by attending retina surgeons. DESIGN: Retrospective comparative case series. PARTICIPANTS: Eight thousand thirty-seven patients treated with intravitreal injection of bevacizumab. METHODS: A retrospective chart review of the resident-performed IVB injections at Rassoul Akram Hospital and attending-performed IVB injections at a private eye clinic between 2011 and 2014 was undertaken. Cases of clinical endophthalmitis were identified. RESULTS: During the study interval, the overall incidence rate of postinjection endophthalmitis was 0.01% (1/8037). Antibiotic eye drops were prescribed after IVB injection for 2771 eyes (34.5%). The single case of acute endophthalmitis occurred after a resident-performed injection, and vitreous culture showed growth of Staphylococcus epidermidis. The incidence rate of acute endophthalmitis after resident-performed IVB injection was 0.02% (1/4921). No statistically significant difference was found in the rates of endophthalmitis between resident-performed and attending-performed injections (p = 1). Also, the difference in the rates of endophthalmitis between those receiving postinjection antibiotics and those who did not was not statistically significant (p = 0.3). CONCLUSIONS: The risk for endophthalmitis after resident-performed IVB injection is low and similar to that of the supervising surgeons performing the procedure.
Authors: Manuel F Bande; Raquel Mansilla; María P Pata; Maribel Fernández; María José Blanco-Teijeiro; Antonio Piñeiro; Francisco Gómez-Ulla Journal: Sci Rep Date: 2017-12-22 Impact factor: 4.379