| Literature DB >> 25676461 |
Michel Klein Gunnewiek1, Andrea Di Luca2, Hermannes Z Bollemaat1, Clemens A van Blitterswijk2,3, G Julius Vancso1, Lorenzo Moroni2,3, Edmondo M Benetti1,4.
Abstract
Coupling of rapid prototyping techniques and surface-confined polymerizations allows the fabrication of 3D multidirectional gradients of biomolecules within microporous scaffolds. The compositional gradients can be tailored by polymer-brush-assisted diffusion of protein solutions. This technique allows spatial control over stem cells manipulation within 3D environments.Entities:
Keywords: 3D scaffolds; poly(ε-caprolactone); polymer brushes; protein gradients; wetting
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Year: 2015 PMID： 25676461 DOI： 10.1002/adhm.201400797
Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933