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Literature DB >> 25675340

Microbacterins A and B, new peptaibols from the deep sea actinomycete Microbacterium sediminis sp. nov. YLB-01(T).

Dong Liu¹, Hong Lin, Peter Proksch, Xixiang Tang, Zhongze Shao, Wenhan Lin.

Abstract

Two new peptaibols, namely microbacterins A (1) and B (2), were isolated from the deep sea inhabited actinomycete Microbacterium sediminis spp. nov. YLB-01(T). The sequences of the amino acid residues were determined on the basis of intensive NMR and ESI-MS/MS spectroscopic analysis, in addition to the Marfey's method and CD and optical rotation data for the configurational assignment. Both 1 and 2 exhibited significant cytotoxic activities against a panel of human tumor cell lines.

Entities: Disease Species

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Year: 2015 PMID： 25675340 DOI： 10.1021/acs.orglett.5b00172

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

13 in total

1. Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics.

Authors: Jin Woo Lee; Jennifer E Collins; Karen L Wendt; Debopam Chakrabarti; Robert H Cichewicz
Journal: J Nat Prod Date: 2021-02-10 Impact factor: 4.050

2. Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides.

Authors: Lin Du; April L Risinger; Carter A Mitchell; Jianlan You; Blake W Stamps; Ning Pan; Jarrod B King; Jean C Bopassa; Susan I V Judge; Zhibo Yang; Bradley S Stevenson; Robert H Cichewicz
Journal: Proc Natl Acad Sci U S A Date: 2017-10-10 Impact factor: 11.205

3. Prealamethicin F50 and related peptaibols from Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis.

Authors: José Rivera-Chávez; Huzefa A Raja; Tyler N Graf; Jacklyn M Gallagher; Prashant Metri; Ding Xue; Cedric J Pearce; Nicholas H Oberlies
Journal: RSC Adv Date: 2017-09-25 Impact factor: 3.361

4. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207.

Authors: Siwen Niu; Ting-Ting Zhou; Chun-Lan Xie; Gai-Yun Zhang; Xian-Wen Yang
Journal: Mar Drugs Date: 2017-07-19 Impact factor: 5.118

10. Microindoline 581, an Indole Derivative from Microbacterium Sp. RP581 as A Novel Selective Antineoplastic Agent to Combat Hepatic Cancer Cells: Production, Optimization and Structural Elucidation.

Authors: Roya Pournejati; Ronald Gust; Brigitte Kircher; Hamid Reza Karbalaei-Heidari
Journal: Iran J Pharm Res Date: 2020 Impact factor: 1.696

Microbacterins A and B, new peptaibols from the deep sea actinomycete Microbacterium sediminis sp. nov. YLB-01(T).

1. Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics.

2. Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides.

3. Prealamethicin F50 and related peptaibols from Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis.

4. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207.

Review 5. Natural Products Research in China From 2015 to 2016.

Review 6. Deep Sea Actinomycetes and Their Secondary Metabolites.

7. Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach.

8. New Ansamycins from the Deep-Sea-Derived Bacterium Ochrobactrum sp. OUCMDZ-2164.

9. Two New Cytotoxic Compounds from a Deep-Sea Penicillum citreonigrum XT20-134.

10. Microindoline 581, an Indole Derivative from Microbacterium Sp. RP581 as A Novel Selective Antineoplastic Agent to Combat Hepatic Cancer Cells: Production, Optimization and Structural Elucidation.