Literature DB >> 25675014

Primary Aspergillus sellar abscess simulating pituitary tumor in immunocompetent patient.

Taohui Ouyang1, Na Zhang, Long Wang, Jiantong Jiao, Yiqing Zhao, Zheng Li, Jian Chen.   

Abstract

A 55-year-old woman presented with headache, dizziness, and decreased visual acuity. Magnetic resonance imaging revealed a sellar mass with sphenoid sinus extension. The result of hormone showed an obviously high prolactin (815 ng/mL). The mass was resected and diagnosed with aspergillosis pathologically. Postoperatively, the level of prolactin dramatically decreased, and the patient received medical treatment with voriconazole and caspofungin. During a 6-month follow-up, the patient's headache and dizziness disappeared, and visual acuity improved. Therefore, aspergillus sellar abscess could result in hyperprolactinemia and should be considered in the differential diagnosis of a sellar mass, even in immunocompetent patients. A combination of surgery and antifungal therapy could reduce the hyperprolactinemia and improve symptoms.

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Year:  2015        PMID: 25675014     DOI: 10.1097/SCS.0000000000001288

Source DB:  PubMed          Journal:  J Craniofac Surg        ISSN: 1049-2275            Impact factor:   1.046


  3 in total

Review 1.  [Hypophysitis : Types and differential diagnosis].

Authors:  W Saeger
Journal:  Pathologe       Date:  2016-05       Impact factor: 1.011

2.  Pituitary abscess: clinical manifestations, diagnosis and treatment of 66 cases from a large pituitary center over 23 years.

Authors:  Lu Gao; Xiaopeng Guo; Rui Tian; Qiang Wang; Ming Feng; Xinjie Bao; Kan Deng; Yong Yao; Wei Lian; Renzhi Wang; Bing Xing
Journal:  Pituitary       Date:  2017-04       Impact factor: 4.107

3.  Fatal case of cerebral aspergilloma complicated by ventriculitis and bacteremia due to Salmonella species in a sickle cell disease patient.

Authors:  Fawzia E Al Otaibi
Journal:  Saudi Med J       Date:  2018-09       Impact factor: 1.484

  3 in total

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