Literature DB >> 25673760

fMRI in analgesic drug discovery.

Tor D Wager1, Choong-Wan Woo2.   

Abstract

Functional magnetic resonance imaging offers an unprecedented opportunity to evaluate and compare drug effects on human brain activity and to provide systems-level predictions for how new drugs for chronic pain will affect the brain, thus accelerating drug discovery and repurposing (Duff et al., this issue).
Copyright © 2015, American Association for the Advancement of Science.

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Year:  2015        PMID： 25673760     DOI： 10.1126/scitranslmed.3010342

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  6 in total

1.  Getting Serious about Variation: Lessons for Clinical Neuroscience (A Commentary on 'The Myth of Optimality in Clinical Neuroscience').

Authors:  Alexander J Shackman; Andrew S Fox
Journal:  Trends Cogn Sci       Date:  2018-03-22       Impact factor: 20.229

Review 2.  Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption.

Authors:  Pradeep J Nathan; Geor Bakker
Journal:  Psychopharmacology (Berl)       Date:  2020-01-04       Impact factor: 4.530

Review 3.  The central extended amygdala in fear and anxiety: Closing the gap between mechanistic and neuroimaging research.

Authors:  Andrew S Fox; Alexander J Shackman
Journal:  Neurosci Lett       Date:  2017-11-30       Impact factor: 3.046

4.  Alterations in brain structure and function in patients with osteonecrosis of the femoral head: a multimodal MRI study.

Authors:  Jie Ma; Jia-Jia Wu; Xu-Yun Hua; Mou-Xiong Zheng; Bei-Bei Huo; Xiang-Xin Xing; Sheng-Yi Feng; Bo Li; Jianguang Xu
Journal:  PeerJ       Date:  2021-08-20       Impact factor: 2.984

Review 5.  Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders.

Authors:  Trang T T Truong; Bruna Panizzutti; Jee Hyun Kim; Ken Walder
Journal:  Pharmaceutics       Date:  2022-07-14       Impact factor: 6.525

6.  Functional magnetic resonance imaging is a powerful approach to probing the mechanism of action of therapeutic drugs that act on the central nervous system.

Authors:  Shu-Feng Zhou
Journal:  Drug Des Devel Ther       Date:  2015-07-23       Impact factor: 4.162
  6 in total

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