Literature DB >> 25670526

Dual emission channels for sensitive discrimination of Cys/Hcy and GSH in plasma and cells.

Yuanlin Zhang1, Xiangmin Shao, Yue Wang, Fuchao Pan, Ruixue Kang, Fangfang Peng, Zhentao Huang, Weijuan Zhang, Weili Zhao.   

Abstract

A new selective fluorescent and colorimetric chemosensor for the detection of GSH was developed. The discrimination of GSH from Cys and Hcy is achieved through two emission channel detection. The detection limit of probe 1 for GSH reached 10 nM (3 ppb). The excellent sensitivity and selectivity of probe 1 allow the selective detection of GSH over Cys and Hcy, which can be visualized colorimetrically and/or fluorescently. The sensitive detection of GSH allowed for convenient measurement of the GSH content in human plasma. The presence of GSH in cells was demonstrated through cell imaging.

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Year:  2015        PMID： 25670526     DOI： 10.1039/c4cc08687b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  pH-Dependent Fluorescent Probe That Can Be Tuned for Cysteine or Homocysteine.

Authors:  Yongkang Yue; Fangjun Huo; Xiaoqi Li; Ying Wen; Tao Yi; James Salamanca; Jorge O Escobedo; Robert M Strongin; Caixia Yin
Journal:  Org Lett       Date:  2016-12-20       Impact factor: 6.005

2.  A Sensitive Ratiometric Long-Wavelength Fluorescent Probe for Selective Determination of Cysteine/Homocysteine.

Authors:  Kesavan Manibalan; Sin-Ming Chen; Veerappan Mani; Tsung-Tao Huang; Sheng-Tung Huang
Journal:  J Fluoresc       Date:  2016-06-11       Impact factor: 2.217

3.  An Ir(III) complex chemosensor for the detection of thiols.

Authors:  Zhifeng Mao; Jinbiao Liu; Tian-Shu Kang; Wanhe Wang; Quan-Bin Han; Chun-Ming Wang; Chung-Hang Leung; Dik-Lung Ma
Journal:  Sci Technol Adv Mater       Date:  2016-04-06       Impact factor: 8.090

4.  Exceptional time response, stability and selectivity in doubly-activated phenyl selenium-based glutathione-selective platform.

Authors:  Youngsam Kim; Sandip V Mulay; Minsuk Choi; Seungyoon B Yu; Sangyong Jon; David G Churchill
Journal:  Chem Sci       Date:  2015-07-09       Impact factor: 9.825

5.  Real time monitoring of aminothiol level in blood using a near-infrared dye assisted deep tissue fluorescence and photoacoustic bimodal imaging.

Authors:  Palapuravan Anees; James Joseph; Sivaramapanicker Sreejith; Nishanth Venugopal Menon; Yuejun Kang; Sidney Wing-Kwong Yu; Ayyappanpillai Ajayaghosh; Yanli Zhao
Journal:  Chem Sci       Date:  2016-03-02       Impact factor: 9.825

6.  A 3,5-dinitropyridin-2yl substituted naphthalimide-based fluorescent probe for the selective detection of biothiols and its application in cell-imaging.

Authors:  Yihua Zhuo; Yanyu Zhang; Yadong Feng; Yuqing Xu; Qihua You; Lei Zhang; Huabin Huang; Lili Lin
Journal:  RSC Adv       Date:  2021-03-01       Impact factor: 3.361

7.  Amphiphilic polymer-encapsulated Au nanoclusters with enhanced emission and stability for highly selective detection of hypochlorous acid.

Authors:  Yiling Li; Shuxiao Yi; Zhongli Lei; Yan Xiao
Journal:  RSC Adv       Date:  2021-04-20       Impact factor: 3.361

8.  A Fluorescent Cy7-Mercaptopyridine for the Selective Detection of Glutathione over Homocysteine and Cysteine.

Authors:  Shin A Yoon; Wantae Kim; Amit Sharma; Peter Verwilst; Miae Won; Min Hee Lee
Journal:  Sensors (Basel)       Date:  2018-09-01       Impact factor: 3.576
  8 in total

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