Literature DB >> 25670368

Long-term clinical results of microsomal triglyceride transfer protein inhibitor use in a patient with homozygous familial hypercholesterolemia.

Anna Raper1, Daniel M Kolansky1, Bruce S Sachais1, Emma A Meagher1, Amanda L Baer1, Marina Cuchel2.   

Abstract

We report the case of a 49-year-old woman with homozygous familial hypercholesterolemia and a complicated cardiovascular history, treated for 5 years with a microsomal triglyceride transfer protein inhibitor in addition to her other lipid-lowering therapy.
Copyright © 2015 National Lipid Association. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  CYP3A4 inhibitors; Cholesterol; Homozygous familial hypercholesterolemia; Liver function tests; Lomitapide; MTP inhibitor; Warfarin

Mesh：

Substances：

Year:  2014        PMID： 25670368      PMCID： PMC4563802          DOI： 10.1016/j.jacl.2014.08.005

Source DB:  PubMed          Journal:  J Clin Lipidol        ISSN： 1876-4789            Impact factor:   4.766


  9 in total

Review 1.  LDL Apheresis: an effective and safe treatment for refractory hypercholesterolemia.

Authors:  Lisa Cooper Hudgins; Bruce R Gordon; Thomas S Parker; Stuart D Saal; Daniel M Levine; Albert L Rubin
Journal:  Cardiovasc Drug Rev       Date:  2002

2.  Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia.

Authors:  Marina Cuchel; LeAnne T Bloedon; Philippe O Szapary; Daniel M Kolansky; Megan L Wolfe; Antoine Sarkis; John S Millar; Katsunori Ikewaki; Evan S Siegelman; Richard E Gregg; Daniel J Rader
Journal:  N Engl J Med       Date:  2007-01-11       Impact factor: 91.245

Review 3.  Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation.

Authors:  Gerald F Watts; Samuel Gidding; Anthony S Wierzbicki; Peter P Toth; Rodrigo Alonso; W Virgil Brown; Eric Bruckert; Joep Defesche; Khoo Kah Lin; Michael Livingston; Pedro Mata; Klaus G Parhofer; Frederick J Raal; Raul D Santos; Eric J G Sijbrands; William G Simpson; David R Sullivan; Andrey V Susekov; Brian Tomlinson; Albert Wiegman; Shizuya Yamashita; John J P Kastelein
Journal:  Int J Cardiol       Date:  2013-11-20       Impact factor: 4.164

Review 4.  Severe hypercholesterolaemia: therapeutic goals and eligibility criteria for LDL apheresis in Europe.

Authors:  Gilbert R Thompson; Alberico Catapano; Samir Saheb; Marielle Atassi-Dumont; Mahmoud Barbir; Mats Eriksson; Bernhard Paulweber; Eric Sijbrands; Anton F Stalenhoef; Klaus G Parhofer
Journal:  Curr Opin Lipidol       Date:  2010-12       Impact factor: 4.776

5.  Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study.

Authors:  Marina Cuchel; Emma A Meagher; Hendrik du Toit Theron; Dirk J Blom; A David Marais; Robert A Hegele; Maurizio R Averna; Cesare R Sirtori; Prediman K Shah; Daniel Gaudet; Claudia Stefanutti; Giovanni B Vigna; Anna M E Du Plessis; Kathleen J Propert; William J Sasiela; LeAnne T Bloedon; Daniel J Rader
Journal:  Lancet       Date:  2012-11-02       Impact factor: 79.321

6.  Pharmacokinetic interactions of the microsomal triglyceride transfer protein inhibitor, lomitapide, with drugs commonly used in the management of hypercholesterolemia.

Authors:  Sony Tuteja; Danielle Duffy; Richard L Dunbar; Rajesh Movva; Ram Gadi; LeAnne T Bloedon; Marina Cuchel
Journal:  Pharmacotherapy       Date:  2014-03       Impact factor: 4.705

7.  Longitudinal evaluation and assessment of cardiovascular disease in patients with homozygous familial hypercholesterolemia.

Authors:  Daniel M Kolansky; Marina Cuchel; Bernard J Clark; Steve Paridon; Brian W McCrindle; Susan E Wiegers; Luis Araujo; Yogesh Vohra; Joep C Defesche; James M Wilson; Daniel J Rader
Journal:  Am J Cardiol       Date:  2008-09-11       Impact factor: 2.778

8.  Correlating corneal arcus with atherosclerosis in familial hypercholesterolemia.

Authors:  Loren A Zech; Jeffery M Hoeg
Journal:  Lipids Health Dis       Date:  2008-03-10       Impact factor: 3.876

9.  Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society.

Authors:  Marina Cuchel; Eric Bruckert; Henry N Ginsberg; Frederick J Raal; Raul D Santos; Robert A Hegele; Jan Albert Kuivenhoven; Børge G Nordestgaard; Olivier S Descamps; Elisabeth Steinhagen-Thiessen; Anne Tybjærg-Hansen; Gerald F Watts; Maurizio Averna; Catherine Boileau; Jan Borén; Alberico L Catapano; Joep C Defesche; G Kees Hovingh; Steve E Humphries; Petri T Kovanen; Luis Masana; Päivi Pajukanta; Klaus G Parhofer; Kausik K Ray; Anton F H Stalenhoef; Erik Stroes; Marja-Riitta Taskinen; Albert Wiegman; Olov Wiklund; M John Chapman
Journal:  Eur Heart J       Date:  2014-07-22       Impact factor: 35.855
  9 in total
  1 in total

Review 1.  Lomitapide-a Microsomal Triglyceride Transfer Protein Inhibitor for Homozygous Familial Hypercholesterolemia.

Authors:  Claudia Stefanutti
Journal:  Curr Atheroscler Rep       Date:  2020-06-18       Impact factor: 5.113
  1 in total

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