Literature DB >> 25670076

Taxane resistance in prostate cancer mediated by AR-independent GATA2 regulation of IGF2.

Stephen R Plymate1, Rupal S Bhatt2, Steven P Balk3.   

Abstract

GATA2 has been well-characterized as a critical pioneer transcription factor for androgen receptor (AR) in prostate cancer. In this issue of Cancer Cell, Vidal and colleagues identify increased GATA2 and its AR-independent transactivation of IGF2 as a mechanism that can mediate taxane resistance through activation of IGF1/insulin receptor signaling.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25670076     DOI： 10.1016/j.ccell.2015.01.008

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  7 in total

1.  Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer.

Authors:  Emmanuel S Antonarakis; Changxue Lu; Brandon Luber; Hao Wang; Yan Chen; Mary Nakazawa; Rosa Nadal; Channing J Paller; Samuel R Denmeade; Michael A Carducci; Mario A Eisenberger; Jun Luo
Journal:  JAMA Oncol       Date:  2015-08       Impact factor: 31.777

2.  Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist.

Authors:  D Ruan; J He; C-F Li; H-J Lee; J Liu; H-K Lin; C-H Chan
Journal:  Oncogene       Date:  2017-03-27       Impact factor: 9.867

3.  Reverse of microtubule-directed chemotherapeutic drugs resistance induced by cancer-associated fibroblasts in breast cancer.

Authors:  Xuebo Li; Qiang Li; Xiuli Yu; Haitao Li; Guoqiang Huang
Journal:  Onco Targets Ther       Date:  2019-09-27       Impact factor: 4.147

4.  Identification of Long Non-Coding RNA Expression Profiles and Co-Expression Genes in Thyroid Carcinoma Based on The Cancer Genome Atlas (TCGA) Database.

Authors:  Yun Zhang; Taobo Jin; Haipeng Shen; Junfeng Yan; Ming Guan; Xin Jin
Journal:  Med Sci Monit       Date:  2019-12-19

5.  Transcriptional dysregulation of TRIM29 promotes colorectal cancer carcinogenesis via pyruvate kinase-mediated glucose metabolism.

Authors:  Jing Han; Zitong Zhao; Nan Zhang; Yang Yang; Liying Ma; Li Feng; Xue Zhang; Jing Zuo; Zhisong Fan; Yudong Wang; Yongmei Song; Guiying Wang
Journal:  Aging (Albany NY)       Date:  2021-01-20       Impact factor: 5.682

6.  Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression.

Authors:  Mahmoud El Maassarani; Alice Barbarin; Gaëlle Fromont; Ouafae Kaissi; Margot Lebbe; Brigitte Vannier; Ahmed Moussa; Paule Séité
Journal:  PLoS One       Date:  2016-05-18       Impact factor: 3.240

7.  Cis-regulatory mechanisms governing stem and progenitor cell transitions.

Authors:  Kirby D Johnson; Guangyao Kong; Xin Gao; Yuan-I Chang; Kyle J Hewitt; Rajendran Sanalkumar; Rajalekshmi Prathibha; Erik A Ranheim; Colin N Dewey; Jing Zhang; Emery H Bresnick
Journal:  Sci Adv       Date:  2015-09-04       Impact factor: 14.136
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.