BACKGROUND: Health-related quality of life (HRQoL) in food-allergic children and their parents can be assessed using generic and specific questionnaires. OBJECTIVES: We investigated whether HRQoL scores in food-allergic children and their parents were similar to normative data and whether they were correlated. METHODS: We searched PubMed, Scopus, and the New York Academy of Medicine Grey Literature Report site. Electronic searches were supplemented by perusal of the references of the papers retrieved. RESULTS: Seventeen studies were eligible. Two studies compared total HRQoL scores for children with food allergy and normative data and found no significant differences. Six studies compared HRQoL questionnaire subdomain scores for children with normative data, and 4 studies compared the same scores for parents with normative data. Children with food allergy scored worse in subdomains including bodily pain, physical functioning, mental health, general health, and emotional, social, and psychological quality of life. However, they performed better in physical health, and had fewer limitations in schoolwork due to behavioral problems. Parents performed better in subdomains such as physical and environmental health, social and psychological health, and family cohesion but scored worse on social health, overall quality of life, emotional health, impact on parental time, and limitations in usual family activities. Statistically significant results for these subdomains were not invariably corroborated by subsequent studies. No study provided data on the correlation between children's HRQoL and that of their parents. CONCLUSIONS: HRQoL of food-allergic children and their parents may differ from that of the normative population in certain subdomains. However, the evidence was not sufficient to draw robust conclusions.
BACKGROUND: Health-related quality of life (HRQoL) in food-allergicchildren and their parents can be assessed using generic and specific questionnaires. OBJECTIVES: We investigated whether HRQoL scores in food-allergicchildren and their parents were similar to normative data and whether they were correlated. METHODS: We searched PubMed, Scopus, and the New York Academy of Medicine Grey Literature Report site. Electronic searches were supplemented by perusal of the references of the papers retrieved. RESULTS: Seventeen studies were eligible. Two studies compared total HRQoL scores for children with food allergy and normative data and found no significant differences. Six studies compared HRQoL questionnaire subdomain scores for children with normative data, and 4 studies compared the same scores for parents with normative data. Children with food allergy scored worse in subdomains including bodily pain, physical functioning, mental health, general health, and emotional, social, and psychological quality of life. However, they performed better in physical health, and had fewer limitations in schoolwork due to behavioral problems. Parents performed better in subdomains such as physical and environmental health, social and psychological health, and family cohesion but scored worse on social health, overall quality of life, emotional health, impact on parental time, and limitations in usual family activities. Statistically significant results for these subdomains were not invariably corroborated by subsequent studies. No study provided data on the correlation between children's HRQoL and that of their parents. CONCLUSIONS: HRQoL of food-allergicchildren and their parents may differ from that of the normative population in certain subdomains. However, the evidence was not sufficient to draw robust conclusions.
Authors: Michael A Golding; Elinor Simons; Elissa M Abrams; Jennifer Gerdts; Jennifer L P Protudjer Journal: Allergy Asthma Clin Immunol Date: 2021-03-10 Impact factor: 3.406