AIM: This work would give an overall and up-to-date vision of psychopharmacological and physical strategies of treatment for resistant depression. METHOD: A PubMed search was done using the keywords "resistant depression treatment", "electroconvulsive therapy", "antidepressants", and the inclusion criteria of adult samples, English, French or Italian languages. RESULTS: Lots of psycho-pharmacological and physical treatment strategies for resistant depression exist; anyway there is no consensus about their indications and efficacy, which appears still unsatisfactory. DISCUSSION AND CONCLUSION: Further research should move towards the identification of specific clinical picture of treatment resistant depression to develop more efficacious and selective treatment protocols.
AIM: This work would give an overall and up-to-date vision of psychopharmacological and physical strategies of treatment for resistant depression. METHOD: A PubMed search was done using the keywords "resistant depression treatment", "electroconvulsive therapy", "antidepressants", and the inclusion criteria of adult samples, English, French or Italian languages. RESULTS: Lots of psycho-pharmacological and physical treatment strategies for resistant depression exist; anyway there is no consensus about their indications and efficacy, which appears still unsatisfactory. DISCUSSION AND CONCLUSION: Further research should move towards the identification of specific clinical picture of treatment resistant depression to develop more efficacious and selective treatment protocols.
Authors: Valentina Perrone; Diego Sangiorgi; Margherita Andretta; Giuseppe Ducci; Bruno Forti; Pier Cesare Francesa Morel; Marco Gambera; Giuseppe Maina; Claudio Mencacci; Francesco Saverio Mennini; Enrico Zanalda; Luca Degli Esposti Journal: Clinicoecon Outcomes Res Date: 2021-07-05