Literature DB >> 25668506

Threatened abortion and late-pregnancy complications: a case-control study and review of literature.

G Petriglia1, I Palaia, A Musella, C Marchetti, M Antonilli, R Brunelli, R Ostuni, P Benedetti Panici.   

Abstract

AIM: Aim of the study was to evaluate the late-pregnancy and perinatal outcomes of patients with threatened miscarriage in the first trimester.
METHODS: An observational cohort study was performed on 81 pregnant women. Subjects were divided into two groups: 1) no bleeding; 2) threatened miscarriage. Patients were followed up until delivery and each materno-fetal complication was registered.
RESULTS: Threatened miscarriage was associated with increased risk of preterm delivery, placenta previa, pregnancy induced hypertension/preeclampsia (PE), low birth weight (LBW) and neonatal intensive care unit (NICU) admission. There were no significantly differences between the 2 groups with regard to preterm prelabour rupture of membranes (PPROM), CESAREAN section, retained placenta, perinatal death and intrauterine growth restriction (IUGR). About immediate neonatal outcomes, mean birth weights were lower (≈ 200 g) in the study group (group 2), while no significant difference in the APGAR score between the two groups was noted.
CONCLUSION: Our study suggests that threatened miscarriage in the first trimester is correlated with an increased incidence of late-pregnancy and perinatal complications and, therefore, these pregnancies should be considered as high risk ones.

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Mesh:

Year:  2015        PMID: 25668506

Source DB:  PubMed          Journal:  Minerva Ginecol        ISSN: 0026-4784


  5 in total

1.  RNA sequencing of chorionic villi from recurrent pregnancy loss patients reveals impaired function of basic nuclear and cellular machinery.

Authors:  Siim Sõber; Kristiina Rull; Mario Reiman; Piret Ilisson; Pirkko Mattila; Maris Laan
Journal:  Sci Rep       Date:  2016-12-08       Impact factor: 4.379

2.  Comparison of the efficacy and safety of phloroglucinol and magnesium sulfate in the treatment of threatened abortion: A meta-analysis of randomized controlled trials.

Authors:  Shaofei Yuan; Fengli Gao; Zhong Xin; Haijun Guo; Suqin Shi; Lei Shi; Xia Yang; Jingzhi Guan
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.889

3.  Association of Single Nucleotide Polymorphisms from Angiogenesis-Related Genes, ANGPT2, TLR2 and TLR9, with Spontaneous Preterm Labor.

Authors:  Wioletta Izabela Wujcicka; Marian Kacerovsky; Adrian Krygier; Michał Krekora; Piotr Kaczmarek; Mariusz Grzesiak
Journal:  Curr Issues Mol Biol       Date:  2022-06-30       Impact factor: 2.976

4.  Sex Hormone Metabolism and Threatened Abortion.

Authors:  Qianhua Xu; Juan Chen; Zhaolian Wei; Theodore R Brandon; David T Zava; Yuenian Eric Shi; Yunxia Cao
Journal:  Med Sci Monit       Date:  2017-10-23

5.  Rs868058 in the Homeobox Gene HLX Contributes to Early-Onset Fetal Growth Restriction.

Authors:  Wioletta Izabela Wujcicka; Marian Kacerovsky; Michał Krekora; Piotr Kaczmarek; Beata Leśniczak; Mariusz Grzesiak
Journal:  Biology (Basel)       Date:  2022-03-16
  5 in total

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