| Literature DB >> 25665943 |
Jiang-Bo He1, Jian Tao2, Xi-Song Miao2, Wei Bu3, Shen Zhang4, Ze-Jun Dong4, Zheng-Hui Li4, Tao Feng5, Ji-Kai Liu6.
Abstract
Seven new drimane-type sesquiterpenoids, sulphureuines B-H (1-7), together with four known compounds (8-11), were obtained from cultures of mushroom Laetiporus sulphureus. All of these compounds were tested for their cytotoxicities against five human cancer cell lines (HL-60, SMMC-721, A-549, MCF-7, SW-480), compound 10 showed potent cytotoxic activity against HL-60, SMMC-721, A-549, SW-480, with IC50 values of 37.5, 14.8, 15.6, and 36.1μM, respectively.Entities:
Keywords: Drimane-type sesquiterpenoids; Laetiporus sulphureus; Sulphureuines B–H
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Year: 2015 PMID: 25665943 DOI: 10.1016/j.fitote.2015.01.022
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882