Literature DB >> 25664711

Is it really small-bowel obstruction in patients with paradox after IPAA?

Jorge Silva-Velazco1, Tracy L Hull, Luca Stocchi, Emre Gorgun.   

Abstract

BACKGROUND: Diagnosing outlet obstruction after IPAA can be challenging because the etiology is multifactorial.
OBJECTIVE: The aim of this study was to assess possible factors associated with outlet obstruction from paradoxical anal muscle contraction (paradox) after IPAA unrelated to strictures or structural abnormalities.
DESIGN: This was a retrospective study from a prospectively maintained pouch database. SETTINGS: The study was conducted at a tertiary referral center. PATIENTS: All of the patients with paradox after ileal J-pouch-anal anastomosis verified by anal physiology were identified from our prospectively maintained database. Patients with endoscopic or digital evidence of strictures or other anatomic abnormalities were excluded. MAIN OUTCOME MEASURES: Demographic, clinical, and perioperative factors were obtained, including previous abdominal operations, history of pouchitis, need for anal intubation, diagnosis of small-bowel obstruction, and radiologic findings at the time of paradox diagnosis.
RESULTS: There were 40 patients (17 women) with an overall mean age of 39 years (range, 17-60 years) and a mean follow-up of 15 years (range, 1-28 years) after IPAA. Pathologic diagnoses at the time of ileal pouch creation were ulcerative colitis (n = 27), indeterminate colitis (n = 11), Crohn's disease, and familial adenomatous polyposis (1 case each). A total of 15 (37%) of 40 patients were diagnosed with small-bowel obstruction before their paradox diagnosis, 8 of whom underwent surgery, which revealed diffusely dilated small bowel and pouch without intraoperative identification of a transition point. The time from ileal pouch creation to paradox diagnosis was significantly longer in patients receiving a diagnosis of small-bowel obstruction than in the remaining paradox patients (7.2 vs 2.6 years; p < 0.001). LIMITATIONS: This study was limited by its nonrandomized retrospective nature.
CONCLUSIONS: After an IPAA, patients with outlet obstruction from paradox can appear to have a small-bowel obstruction. A high incidence of suspicion is needed to make the correct diagnosis and avoid an unneeded laparotomy.

Entities:  

Mesh:

Year:  2015        PMID: 25664711     DOI: 10.1097/DCR.0000000000000264

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  2 in total

1.  Ileal pouch functional outlet obstruction.

Authors:  Kyra Sierakowski; Philippa Rabbitt; David Wattchow
Journal:  BMJ Case Rep       Date:  2016-02-08

2.  Characterization of megapouch in patients with restorative proctocolectomy.

Authors:  Preeti Shashi; Bo Shen
Journal:  Surg Endosc       Date:  2018-10-16       Impact factor: 4.584

  2 in total

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