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Literature DB >> 25664005

Role of cancer stem cell marker CD44 in gastric cancer: a meta-analysis.

Wei Wang¹, Li-Ping Dong², Ning Zhang¹, Cheng-Hai Zhao¹.

Abstract

Cluster of differentiation 44 (CD44), a principal cell surface receptor for hyaluronic acid, has been implicated in tumorigenesis and metastasis. However, the relationship between CD44 expression and the patients with gastric cancer remains controversial. A meta-analysis was performed to quantitatively review the correlation of CD44 expression with the clinicopathological data of the patients with gastric cancer. We conducted a final analysis of the patients from 18 studies. Combined odds ratios (OR) suggested that CD44 expression was related with stage, tumor size, and LN metastasis of gastric cancer, and CD44v6 was related with LN metastasis, lymphatic invasion, and venous invasion. Our results suggested that CD44 and CD44v6 expression could be used to predict the metastasis of gastric cancer.

Entities: Chemical Disease Species

Keywords: CD44; gastric cancer; invasion; metastasis; tumorigenesis

Year: 2014 PMID： 25664005 PMCID： PMC4307452

Source DB: PubMed Journal: Int J Clin Exp Med ISSN： 1940-5901

33 in total

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Journal: Int J Oncol Date: 2000-11 Impact factor: 5.650

2. Isolation and DNA sequence of a cDNA clone encoding a lymphocyte adhesion receptor for high endothelium.

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Journal: Proc Natl Acad Sci U S A Date: 1989-06 Impact factor: 11.205

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Journal: Nature Date: 1983 Jul 7-13 Impact factor: 49.962

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Authors: Akio Yamaguchi; Takanori Goi; Jiren Yu; Yasuo Hirono; Makoto Ishida; Atsushi Iida; Toshihisa Kimura; Kazuo Takeuchi; Kanji Katayama; Kazuo Hirose
Journal: J Surg Oncol Date: 2002-04 Impact factor: 3.454

Review 5. Incidence and mortality of gastric cancer in China.

Authors: Ling Yang
Journal: World J Gastroenterol Date: 2006-01-07 Impact factor: 5.742

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Journal: J Pathol Date: 1997-10 Impact factor: 7.996

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Journal: Proc Natl Acad Sci U S A Date: 1992-12-15 Impact factor: 11.205

8. Genetic association of osteopontin (OPN) and its receptor CD44 genes with susceptibility to Chinese gastric cancer patients.

Authors: Yue Qiu; Yuan Hu; Zuo-Yang Zhang; Lei Ye; Fei-Hong Xu; Marion E Schneider; Xue-Ling Ma; Yi-Xin Du; Xian-Bo Zuo; Fu-Sheng Zhou; Gang Chen; Xu-Shi Xie; Yan Zhang; Hong-Zhen Xia; Ji-Feng Wu; Wei-Dong Du
Journal: J Cancer Res Clin Oncol Date: 2014-07-10 Impact factor: 4.553

Review 9. Gastric cancer stem cells in gastric carcinogenesis, progression, prevention and treatment.

Authors: Kang Li; Zeng Dan; Yu-Qiang Nie
Journal: World J Gastroenterol Date: 2014-05-14 Impact factor: 5.742

10. Expression of CD44 variant 6 and lymphatic invasion: importance to lymph node metastasis in gastric cancer.

Authors: K Kurozumi; T Nishida; K Nakao; M Nakahara; M Tsujimoto
Journal: World J Surg Date: 1998-08 Impact factor: 3.352

27 in total

1. Reduced expression of the long non-coding RNA AI364715 in gastric cancer and its clinical significance.

Authors: Shengqian Zhu; Jinqin Mao; Yongfu Shao; Fang Chen; Xiaoqin Zhu; Dingli Xu; Xinjun Zhang; Junming Guo
Journal: Tumour Biol Date: 2015-05-14

2. Mesenchymal subtype of glioblastomas with high DNA-PKcs expression is associated with better response to radiotherapy and temozolomide.

Authors: Baptiste Pinel; Mathilde Duchesne; Julie Godet; Serge Milin; Antoine Berger; Michel Wager; Lucie Karayan-Tapon
Journal: J Neurooncol Date: 2017-01-10 Impact factor: 4.130

Review 3. Mechanisms of tumor cell resistance to the current targeted-therapy agents.

Authors: Gholamreza Khamisipour; Farhad Jadidi-Niaragh; Abdolreza Sotoodeh Jahromi; Keivan Zandi; Mohammad Hojjat-Farsangi
Journal: Tumour Biol Date: 2016-05-07

Review 4. Gastric cancer stem cells: evidence, potential markers, and clinical implications.

Authors: Daniel Brungs; Morteza Aghmesheh; Kara L Vine; Therese M Becker; Martin G Carolan; Marie Ranson
Journal: J Gastroenterol Date: 2015-10-01 Impact factor: 7.527

5. Expression of CD44⁺/CD24^-, RAD6 and DDB2 on chemotherapy response in ovarian Cancer: A prospective flow cytometry study.

Authors: Unedo Hence Markus Sihombing; Gatot Purwoto; Supriadi Gandamihardja; Alida R Harahap; Primariadewi Rustamadji; Aria Kekalih; Retno Widyawati; Dzicky Rifqi Fuady
Journal: Gynecol Oncol Rep Date: 2022-06-03