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Literature DB >> 25663759

Management of perianal fistulas in Crohn's disease: an up-to-date review.

Manuela Marzo¹, Carla Felice¹, Daniela Pugliese¹, Gianluca Andrisani¹, Giammarco Mocci¹, Alessandro Armuzzi¹, Luisa Guidi¹.

Abstract

Perianal disease is one of the most disabling manifestations of Crohn's disease. A multidisciplinary approach of gastroenterologist, colorectal surgeon and radiologist is necessary for its management. A correct diagnosis, based on endoscopy, magnetic resonance imaging, endoanal ultrasound and examination under anesthesia, is crucial for perianal fistula treatment. Available medical and surgical therapies are discussed in this review, including new local treatment modalities that are under investigation.

Entities: Disease

Keywords: Crohn’s disease; Drug therapy; Perianal fistula; Surgery; Tumor necrosis factor alpha

Mesh：

Year: 2015 PMID： 25663759 PMCID： PMC4316082 DOI： 10.3748/wjg.v21.i5.1394

Source DB: PubMed Journal: World J Gastroenterol ISSN： 1007-9327 Impact factor: 5.742

87 in total

Review 1. AGA technical review on perianal Crohn's disease.

Authors: William J Sandborn; Victor W Fazio; Brian G Feagan; Stephen B Hanauer
Journal: Gastroenterology Date: 2003-11 Impact factor: 22.682

2. A unique 3D endoanal ultrasound feature of perianal Crohn's fistula: the 'Crohn ultrasound fistula sign'.

Authors: A Zawadzki; M Starck; M Bohe; H Thorlacius
Journal: Colorectal Dis Date: 2012-09 Impact factor: 3.788

3. Local injection of adalimumab for perianal Crohn's disease: better than infliximab?

Authors: G Poggioli; S Laureti; F Pierangeli; P Bazzi; M Coscia; L Gentilini; P Gionchetti; F Rizzello
Journal: Inflamm Bowel Dis Date: 2010-10 Impact factor: 5.325

4. Clinical advantages of combined seton placement and infliximab maintenance therapy for perianal fistulizing Crohn's disease: when and how were the seton drains removed?

Authors: Shinnosuke Tanaka; Katsuichi Matsuo; Takamitsu Sasaki; Masahiko Nakano; Koutarou Sakai; Richiko Beppu; Yuichi Yamashita; Kazuhiro Maeda; Kunihiko Aoyagi
Journal: Hepatogastroenterology Date: 2010 Jan-Feb

5. A classification of fistula-in-ano.

Authors: A G Parks; P H Gordon; J D Hardcastle
Journal: Br J Surg Date: 1976-01 Impact factor: 6.939

6. Fibrin glue is effective healing perianal fistulas in patients with Crohn's disease.

Authors: Jean-Charles Grimaud; Nicolas Munoz-Bongrand; Laurent Siproudhis; Laurent Abramowitz; Agnès Sénéjoux; Véronique Vitton; Luc Gambiez; Bernard Flourié; Xavier Hébuterne; Edouard Louis; Benoit Coffin; Vincent De Parades; Guillaume Savoye; Jean-Claude Soulé; Yoram Bouhnik; Jean-Frédéric Colombel; Jean-François Contou; Yves François; Jean-Yves Mary; Marc Lémann
Journal: Gastroenterology Date: 2010-02-20 Impact factor: 22.682

Review 7. Pathophysiology of fistula formation in Crohn's disease.

Authors: Michael Scharl; Gerhard Rogler
Journal: World J Gastrointest Pathophysiol Date: 2014-08-15

8. Clinical outcome following treatment of refractory inflammatory and fistulizing Crohn's disease with intravenous cyclosporine.

Authors: L J Egan; W J Sandborn; W J Tremaine
Journal: Am J Gastroenterol Date: 1998-03 Impact factor: 10.864

9. Usual therapy improves perianal Crohn's disease as measured by a new disease activity index. McMaster IBD Study Group.

Authors: E J Irvine
Journal: J Clin Gastroenterol Date: 1995-01 Impact factor: 3.062

10. A prospective evaluation of the ligation of the intersphincteric tract procedure for complex anal fistula in patients with Crohn's disease.

Authors: Daniel S Gingold; Zuri A Murrell; Phillip R Fleshner
Journal: Ann Surg Date: 2014-12 Impact factor: 12.969

29 in total

Review 1. Prognostic factors affecting outcomes in fistulating perianal Crohn's disease: a systematic review.

Authors: G C Braithwaite; M J Lee; D Hind; S R Brown
Journal: Tech Coloproctol Date: 2017-06-20 Impact factor: 3.781

Review 2. British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.

Authors: Christopher Andrew Lamb; Nicholas A Kennedy; Tim Raine; Philip Anthony Hendy; Philip J Smith; Jimmy K Limdi; Bu'Hussain Hayee; Miranda C E Lomer; Gareth C Parkes; Christian Selinger; Kevin J Barrett; R Justin Davies; Cathy Bennett; Stuart Gittens; Malcolm G Dunlop; Omar Faiz; Aileen Fraser; Vikki Garrick; Paul D Johnston; Miles Parkes; Jeremy Sanderson; Helen Terry; Daniel R Gaya; Tariq H Iqbal; Stuart A Taylor; Melissa Smith; Matthew Brookes; Richard Hansen; A Barney Hawthorne
Journal: Gut Date: 2019-09-27 Impact factor: 23.059

Review 3. Pathogenesis and persistence of cryptoglandular anal fistula: a systematic review.

Authors: Jeremy Sugrue; Johan Nordenstam; Herand Abcarian; Amelia Bartholomew; Joel L Schwartz; Anders Mellgren; Philip J Tozer
Journal: Tech Coloproctol Date: 2017-06-15 Impact factor: 3.781

Review 4. Pharmacological Approach to the Management of Crohn's Disease Patients with Perianal Disease.

Authors: Fernando Bermejo; Iván Guerra; Alicia Algaba; Antonio López-Sanromán
Journal: Drugs Date: 2018-01 Impact factor: 9.546

Review 5. What is the optimal surgical strategy for complex perianal fistulous disease in pediatric Crohn's disease? A systematic review.

Authors: Navot Kantor; Carolyn Wayne; Ahmed Nasr
Journal: Pediatr Surg Int Date: 2017-01-30 Impact factor: 1.827

6. Guidelines for the management of patients with Crohn's disease. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology.

Authors: Michał Łodyga; Piotr Eder; Magdalena Gawron-Kiszka; Agnieszka Dobrowolska; Maciej Gonciarz; Marek Hartleb; Maria Kłopocka; Ewa Małecka-Wojciesko; Piotr Radwan; Jarosław Reguła; Edyta Zagórowicz; Grażyna Rydzewska
Journal: Prz Gastroenterol Date: 2021-11-19