Literature DB >> 25662990

Does UTI cause prolonged jaundice in otherwise well infants?

Tanzila Chowdhury1, Hamudi Kisat, Kjell Tullus.   

Abstract

UNLABELLED: The symptoms of urinary tract infections in infants are very non-specific and have historically included prolonged hyperbilirubinaemia. We studied the results of routine urine samples in 319 infants with prolonged jaundice. Convincing findings of UTI was not found in any of these children even if one of them was treated with antibiotics after four consecutive urine cultures with different bacteria.
CONCLUSION: A urine culture might thus not be an appropriate investigation in a child with prolonged jaundice without any other symptoms of UTI. WHAT IS KNOWN: • The symptoms of UTI in infancy are very non-specific. • Old studies suggest that prolonged hyperbilirubinaemia is one such symptom; more modern studies give more conflicting results. What is New: • Our study could not confirm that children with prolonged jaundice have an increased risk of UTI. • Routine urine testing is thus not needed in otherwise healthy infants with prolonged jaundice.

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Year:  2015        PMID: 25662990     DOI: 10.1007/s00431-015-2499-3

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  9 in total

1.  NICE recommendations for the formal assessment of babies with prolonged jaundice: too much for well infants?

Authors:  M E Rodie; A Barclay; C Harry; J Simpson
Journal:  Arch Dis Child       Date:  2010-10-27       Impact factor: 3.791

Review 2.  Febrile urinary tract infections in children.

Authors:  Giovanni Montini; Kjell Tullus; Ian Hewitt
Journal:  N Engl J Med       Date:  2011-07-21       Impact factor: 91.245

3.  Urinary tract infections presenting with jaundice.

Authors:  S H Ng; J R Rawstron
Journal:  Arch Dis Child       Date:  1971-04       Impact factor: 3.791

4.  Urine collection from infants: a reliable method.

Authors:  S Vernon
Journal:  Paediatr Nurs       Date:  1995-07

5.  Jaundice as an early diagnostic sign of urinary tract infection in infancy.

Authors:  Francisco J Garcia; Alan L Nager
Journal:  Pediatrics       Date:  2002-05       Impact factor: 7.124

6.  Investigation of prolonged neonatal jaundice.

Authors:  S Hannam; M McDonnell; J M Rennie
Journal:  Acta Paediatr       Date:  2000-06       Impact factor: 2.299

7.  Unexplained neonatal jaundice as an early diagnostic sign of urinary tract infection.

Authors:  Mozhgan Shahian; Parisa Rashtian; Mehdi Kalani
Journal:  Int J Infect Dis       Date:  2012-04-16       Impact factor: 3.623

8.  Urinary tract infection in term neonates with prolonged jaundice.

Authors:  Nader Pashapour; Ahmad Ali Nikibahksh; Sariyeh Golmohammadlou
Journal:  Urol J       Date:  2007       Impact factor: 1.510

9.  Urinary tract infections in neonates with jaundice in their first two weeks of life.

Authors:  Mehmet Mutlu; Yasemin Cayır; Yakup Aslan
Journal:  World J Pediatr       Date:  2013-10-21       Impact factor: 2.764

  9 in total
  2 in total

1.  The debate continues: is urine culture indicated in neonates with prolonged jaundice?

Authors:  Siba Prosad Paul; Emily Natasha Kirkham
Journal:  Eur J Pediatr       Date:  2016-02-17       Impact factor: 3.183

2.  Reply to: Paul SP, et al. (2016) the debate continues: is urine culture indicated in neonates with prolonged jaundice?

Authors:  Kjell Tullus
Journal:  Eur J Pediatr       Date:  2016-06       Impact factor: 3.183

  2 in total

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