BACKGROUND: Studies assessing the association between coeliac disease (CD) and psoriasis show conflicting results. OBJECTIVE: To assess in the primary care setting the prevalence of CD in patients with psoriasis and the response to a gluten-free diet (GFD) in subjects with psoriasis and CD. METHODS: We enrolled 218 patients with psoriasis and 264 controls. Coeliac screening was carried out in all subjects (Eurospital, Trieste, Italy). In subjects with a positive serology, the diagnosis of CD was confirmed histologically. RESULTS: Nine (4.1%) psoriatic patients had positive anti-tissue transglutaminase antibodies compared to only 1 among controls (0.4%, p < 0.05; OR 2.03, 95% CI 1.42-90.11). The diagnosis of CD was confirmed histologically in all 10 subjects. At 6 months GFD was associated with a great improvement of skin lesions in 7 out of 8 patients with psoriasis. CONCLUSION: Our multicentre primary care study showed an high prevalence of CD in psoriasis and an improvement of skin lesions in CD under GFD.
BACKGROUND: Studies assessing the association between coeliac disease (CD) and psoriasis show conflicting results. OBJECTIVE: To assess in the primary care setting the prevalence of CD in patients with psoriasis and the response to a gluten-free diet (GFD) in subjects with psoriasis and CD. METHODS: We enrolled 218 patients with psoriasis and 264 controls. Coeliac screening was carried out in all subjects (Eurospital, Trieste, Italy). In subjects with a positive serology, the diagnosis of CD was confirmed histologically. RESULTS: Nine (4.1%) psoriaticpatients had positive anti-tissue transglutaminase antibodies compared to only 1 among controls (0.4%, p < 0.05; OR 2.03, 95% CI 1.42-90.11). The diagnosis of CD was confirmed histologically in all 10 subjects. At 6 months GFD was associated with a great improvement of skin lesions in 7 out of 8 patients with psoriasis. CONCLUSION: Our multicentre primary care study showed an high prevalence of CD in psoriasis and an improvement of skin lesions in CD under GFD.
Authors: Ladan Afifi; Melissa J Danesh; Kristina M Lee; Kevin Beroukhim; Benjamin Farahnik; Richard S Ahn; Di Yan; Rasnik K Singh; Mio Nakamura; John Koo; Wilson Liao Journal: Dermatol Ther (Heidelb) Date: 2017-05-19
Authors: Nikolai A Kolchak; Maria K Tetarnikova; Maria S Theodoropoulou; Alexandra P Michalopoulou; Demetrios S Theodoropoulos Journal: J Multidiscip Healthc Date: 2017-12-27
Authors: Ludovico Abenavoli; Stefano Dastoli; Luigi Bennardo; Luigi Boccuto; Maria Passante; Martina Silvestri; Ilaria Proietti; Concetta Potenza; Francesco Luzza; Steven Paul Nisticò Journal: Medicina (Kaunas) Date: 2019-09-09 Impact factor: 2.430