Literature DB >> 25662522

Testing for meningitis in children with bronchiolitis.

Michael Stefanski1, Ronald Williams2, George McSherry3, Joseph Geskey4.   

Abstract

Viral bronchiolitis accounts for almost 20% of all-cause hospitalizations of infants (ie, children younger than age 1 year). The annual incidence of fever in viral bronchiolitis has been documented at 23% to 31%. However the incidence of concurrent serious bacterial infections is low (1%-7%), with meningitis occurring in less than 1% to 2% of cases, but lumbar puncture is performed in up to 9% of viral bronchiolitis cases. To our knowledge, no study has examined clinical factors that influence a physician’s decision to perform a lumbar puncture in the setting of viral bronchiolitis. We present a retrospective, case-control study of hospitalized infants younger than one year diagnosed with viral bronchiolitis who underwent lumbar puncture as part of an evaluation for meningitis. The objective of the study was to determine clinical factors that influence a physician’s decision to perform a lumbar puncture in the setting of viral bronchiolitis. Although the presence of apnea, cyanosis, meningeal signs, positive urine culture results, and young age were factors found to be preliminarily associated with the performance of a lumbar puncture in the setting of bronchiolitis, young age was the only significant clinical factor found after multivariable regression; no other demographic, clinical, laboratory, or radiologic variables were found to be significant.

Entities:  

Mesh:

Year:  2014        PMID: 25662522      PMCID: PMC4206166          DOI: 10.7812/TPP/14-015

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  25 in total

1.  Concurrent meningitis/serious bacterial infection in an infant hospitalized with respiratory syncytial virus.

Authors:  Robert S McGregor; Jeanne Tung
Journal:  Arch Pediatr Adolesc Med       Date:  2002-10

2.  Longitudinal data analysis for discrete and continuous outcomes.

Authors:  S L Zeger; K Y Liang
Journal:  Biometrics       Date:  1986-03       Impact factor: 2.571

3.  Bronchiolitis-associated hospitalizations among US children, 1980-1996.

Authors:  D K Shay; R C Holman; R D Newman; L L Liu; J W Stout; L J Anderson
Journal:  JAMA       Date:  1999-10-20       Impact factor: 56.272

4.  Concurrent serious bacterial infections in 2396 infants and children hospitalized with respiratory syncytial virus lower respiratory tract infections.

Authors:  Kevin Purcell; Jaime Fergie
Journal:  Arch Pediatr Adolesc Med       Date:  2002-04

5.  Enhanced urinalysis improves identification of febrile infants ages 60 days and younger at low risk for serious bacterial illness.

Authors:  S M Herr; E R Wald; R D Pitetti; S S Choi
Journal:  Pediatrics       Date:  2001-10       Impact factor: 7.124

6.  Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis.

Authors:  Elliot Melendez; Marvin B Harper
Journal:  Pediatr Infect Dis J       Date:  2003-12       Impact factor: 2.129

7.  Identification of infants unlikely to have serious bacterial infection although hospitalized for suspected sepsis.

Authors:  R Dagan; K R Powell; C B Hall; M A Menegus
Journal:  J Pediatr       Date:  1985-12       Impact factor: 4.406

8.  Prevalence of serious bacterial infections in febrile infants with respiratory syncytial virus infection.

Authors:  M Olivia Titus; Seth W Wright
Journal:  Pediatrics       Date:  2003-08       Impact factor: 7.124

9.  Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections.

Authors:  Deborah A Levine; Shari L Platt; Peter S Dayan; Charles G Macias; Joseph J Zorc; William Krief; Jeffrey Schor; David Bank; Nancy Fefferman; Kathy N Shaw; Nathan Kuppermann
Journal:  Pediatrics       Date:  2004-06       Impact factor: 7.124

10.  Outpatient treatment of febrile infants 28 to 89 days of age with intramuscular administration of ceftriaxone.

Authors:  M N Baskin; E J O'Rourke; G R Fleisher
Journal:  J Pediatr       Date:  1992-01       Impact factor: 4.406

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