Literature DB >> 25662322

Finding the evidence for pulmonary metastasectomy in colorectal cancer: the PulMicc trial.

Marcello Migliore1, Mišel Milošević, Belinda Lees, Tom Treasure, Giuseppe Di Maria.   

Abstract

The PulMiCC trial is a randomized controlled trial testing the effect on survival of pulmonary metastasectomy in patients with colorectal cancer. In stage 1 of the trial patients with treated primary colorectal cancer metastatic to the lungs are invited to consent for protocol-based evaluation of their suitability for metastasectomy. The evaluation is as in current practice and includes PET/CT. A decision for or against metastasectomy may be based on the opinion of the clinicians and the preference of the patient. If there is uncertainty the patient is invited to consent to have the treatment arm assigned by randomization in stage 2 of PulMiCC. More than 300 patients have entered stage 1 and more than 70 are in stage 2.

Entities:  

Keywords:  colorectal cancer; lung metastasectomy; randomized trial

Mesh:

Year:  2015        PMID: 25662322     DOI: 10.2217/fon.14.207

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


  5 in total

Review 1.  Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure?

Authors:  Camille L Stewart; Susanne Warner; Kaori Ito; Mustafa Raoof; Geena X Wu; Jonathan Kessler; Jae Y Kim; Yuman Fong
Journal:  Curr Probl Surg       Date:  2018-10-04       Impact factor: 1.909

2.  Looking forward lung metastasectomy-do we need a staging system for lung metastases?

Authors:  Marcello Migliore; Michel Gonzalez
Journal:  Ann Transl Med       Date:  2016-03

Review 3.  Systemic Versus Local Therapies for Colorectal Cancer Pulmonary Metastasis: What to Choose and When?

Authors:  Tony Ibrahim; Lambros Tselikas; Charbel Yazbeck; Joseph Kattan
Journal:  J Gastrointest Cancer       Date:  2016-09

Review 4.  Surveillance after curative treatment for colorectal cancer.

Authors:  Eric P van der Stok; Manon C W Spaander; Dirk J Grünhagen; Cornelis Verhoef; Ernst J Kuipers
Journal:  Nat Rev Clin Oncol       Date:  2016-12-20       Impact factor: 66.675

5.  How surgical care is changing in the technological era.

Authors:  Marcello Migliore
Journal:  Future Sci OA       Date:  2016-03-16
  5 in total

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