| Literature DB >> 25660470 |
Naoshi Hiramatsu1, Takashi Todo2, Craig V Sullivan3, Justin Schilling4, Benjamin J Reading4, Takahiro Matsubara5, Yong-Woon Ryu6, Hiroko Mizuta7, Wenshu Luo8, Osamu Nishimiya7, Meiqin Wu7, Yuji Mushirobira7, Ozlem Yilmaz9, Akihiko Hara2.
Abstract
Fish egg yolk is largely derived from vitellogenins, which are synthesized in the liver, taken up from the maternal circulation by growing oocytes via receptor-mediated endocytosis and enzymatically processed into yolk proteins that are stored in the ooplasm. Lipid droplets are another major component of fish egg yolk, and these are mainly composed of neutral lipids that may originate from maternal plasma lipoproteins. This review aims to briefly summarize our current understanding of the molecular mechanisms underlying yolk formation in fishes. A hypothetical model of oocyte growth is proposed based on recent advances in our knowledge of fish yolk formation.Entities:
Keywords: Fish; Lipoprotein receptors; Lipoproteins; Oocyte; Vitellogenins; Yolk
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Year: 2015 PMID： 25660470 DOI： 10.1016/j.ygcen.2015.01.025
Source DB: PubMed Journal: Gen Comp Endocrinol ISSN： 0016-6480 Impact factor: 2.822