Hong-Wei Wang1, Xing-Jun Qin2, Wen-Jun Yang3, Li-Qun Xu3, Tong Ji3, Chen-Ping Zhang3. 1. Master Student, Department of Oral and Maxillofacial-Head and Neck Oncology, 9th People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2. Associate Professor, Department of Oral and Maxillofacial-Head and Neck Oncology, 9th People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: Qinxj1989@sina.cn. 3. Professor, Department of Oral and Maxillofacial-Head and Neck Oncology, 9th People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Abstract
OBJECTIVES: To summarize the clinical features, diagnosis, treatment strategies, and prognosis of alveolar soft part sarcoma (ASPS) of the oral and maxillofacial region. STUDY DESIGN: We performed a retrospective study in a consecutive series of 18 patients with ASPS of the oral and maxillofacial region between 1995 and 2013. Demographic characteristics, tumor sizes, sites, tumor metastasis, diagnosis, treatments, and overall follow-ups were documented. RESULTS: The 18 patients were diagnosed pathologically with primary tumor developed on the tongue (10), the cheek (5), the pharynx (1), and the gingiva (2) with an average tumor size of 4 cm. At the latest follow-up, 1 patient with lung metastases survived for 23 months; 1 died 3 months after the confirmation of local recurrence and multiple pulmonary metastases; the rest of the patients were disease free and remained in good health. CONCLUSIONS: ASPS of the oral and maxillofacial region appears to have special clinical characteristics.
OBJECTIVES: To summarize the clinical features, diagnosis, treatment strategies, and prognosis of alveolar soft part sarcoma (ASPS) of the oral and maxillofacial region. STUDY DESIGN: We performed a retrospective study in a consecutive series of 18 patients with ASPS of the oral and maxillofacial region between 1995 and 2013. Demographic characteristics, tumor sizes, sites, tumor metastasis, diagnosis, treatments, and overall follow-ups were documented. RESULTS: The 18 patients were diagnosed pathologically with primary tumor developed on the tongue (10), the cheek (5), the pharynx (1), and the gingiva (2) with an average tumor size of 4 cm. At the latest follow-up, 1 patient with lung metastases survived for 23 months; 1 died 3 months after the confirmation of local recurrence and multiple pulmonary metastases; the rest of the patients were disease free and remained in good health. CONCLUSIONS:ASPS of the oral and maxillofacial region appears to have special clinical characteristics.