Nilima Kumar1, Kavitha Prasad2, Laitha Ramanujam3, Ranganath K4, Jayashree Dexith5, Abhishek Chauhan6. 1. PG Trainee, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India. Electronic address: nilima.kumar@rediffmail.com. 2. Professor and Department Head, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India. 3. Senior Professor, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India. 4. Professor, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India. 5. Reader, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India. 6. PG Trainee, Department of Oral and Maxillofacial Surgery, M.S. Ramaiah Dental College and Hospital, Bangalore, Karnataka, India.
Abstract
PURPOSE: To assess the effect of platelet-rich fibrin (PRF) on postoperative pain, swelling, trismus, periodontal healing on the distal aspect of the second molar, and progress of bone regeneration in mandibular third molar extraction sockets. MATERIALS AND METHODS: Over a 2-year period, 31 patients (mean age, 26.1 yr) who required surgical extraction of a single impacted third molar and met the inclusion criteria were recruited. After surgical extraction of the third molar, only primary closure was performed in the control group, whereas PRF was placed in the socket followed by primary closure in the case group (16 patients). The outcome variables were pain, swelling, maximum mouth opening, periodontal pocket depth, and bone formation, with a follow-up period of 3 months. Quantitative data are presented as mean. Statistical significance was inferred at a P value less than .05. RESULTS:Pain (P = .017), swelling (P = .022), and interincisal distance (P = .040) were less in the case group compared with the control group on the first postoperative day. Periodontal pocket depth decreased at 3 months postoperatively in the case (P < .001) and control (P = .014) groups, and this decrease was statistically significant. Bone density scores at 3 months postoperatively were higher in the case group than in the control group, but this difference was not statistically important. CONCLUSIONS: The application of PRF lessens the severity of immediate postoperative sequelae, decreases preoperative pocket depth, and hastens bone formation.
RCT Entities:
PURPOSE: To assess the effect of platelet-rich fibrin (PRF) on postoperative pain, swelling, trismus, periodontal healing on the distal aspect of the second molar, and progress of bone regeneration in mandibular third molar extraction sockets. MATERIALS AND METHODS: Over a 2-year period, 31 patients (mean age, 26.1 yr) who required surgical extraction of a single impacted third molar and met the inclusion criteria were recruited. After surgical extraction of the third molar, only primary closure was performed in the control group, whereas PRF was placed in the socket followed by primary closure in the case group (16 patients). The outcome variables were pain, swelling, maximum mouth opening, periodontal pocket depth, and bone formation, with a follow-up period of 3 months. Quantitative data are presented as mean. Statistical significance was inferred at a P value less than .05. RESULTS:Pain (P = .017), swelling (P = .022), and interincisal distance (P = .040) were less in the case group compared with the control group on the first postoperative day. Periodontal pocket depth decreased at 3 months postoperatively in the case (P < .001) and control (P = .014) groups, and this decrease was statistically significant. Bone density scores at 3 months postoperatively were higher in the case group than in the control group, but this difference was not statistically important. CONCLUSIONS: The application of PRF lessens the severity of immediate postoperative sequelae, decreases preoperative pocket depth, and hastens bone formation.
Authors: Ana B Castro; Nastaran Meschi; Andy Temmerman; Nelson Pinto; Paul Lambrechts; Wim Teughels; Marc Quirynen Journal: J Clin Periodontol Date: 2017-01-10 Impact factor: 8.728
Authors: Edmund Bailey; Wafa Kashbour; Neha Shah; Helen V Worthington; Tara F Renton; Paul Coulthard Journal: Cochrane Database Syst Rev Date: 2020-07-26
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