Literature DB >> 25656706

Dynamics of B cells in germinal centres.

Nilushi S De Silva1, Ulf Klein1.   

Abstract

Humoral immunity depends on the germinal centre (GC) reaction during which somatically mutated high-affinity memory B cells and plasma cells are generated. Recent studies have uncovered crucial cues that are required for the formation and the maintenance of GCs and for the selection of high-affinity antibody mutants. In addition, it is now clear that these events are promoted by the dynamic movements of cells within and between GCs. These findings have resolved the complexities of the GC reaction in greater detail than ever before. This Review focuses on these recent advances and discusses their implications for the establishment of humoral immunity.

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Year:  2015        PMID： 25656706      PMCID： PMC4399774          DOI： 10.1038/nri3804

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  116 in total

Review 1.  Germinal center selection and the development of memory B and plasma cells.

Authors:  Mark J Shlomchik; Florian Weisel
Journal:  Immunol Rev       Date:  2012-05       Impact factor: 12.988

Review 2.  Roles of BCL6 in normal and transformed germinal center B cells.

Authors:  Katia Basso; Riccardo Dalla-Favera
Journal:  Immunol Rev       Date:  2012-05       Impact factor: 12.988

Review 3.  Determining germinal centre B cell fate.

Authors:  Dimitra Zotos; David M Tarlinton
Journal:  Trends Immunol       Date:  2012-05-16       Impact factor: 16.687

Review 4.  Germinal centres and B cell lymphomagenesis.

Authors:  Katia Basso; Riccardo Dalla-Favera
Journal:  Nat Rev Immunol       Date:  2015-03       Impact factor: 53.106

5.  T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction.

Authors:  Dan Liu; Heping Xu; Changming Shih; Zurong Wan; Xiaopeng Ma; Weiwei Ma; Dan Luo; Hai Qi
Journal:  Nature       Date:  2014-10-15       Impact factor: 49.962

Review 6.  The diverse roles of IRF4 in late germinal center B-cell differentiation.

Authors:  Nilushi S De Silva; Giorgia Simonetti; Nicole Heise; Ulf Klein
Journal:  Immunol Rev       Date:  2012-05       Impact factor: 12.988

7.  B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity.

Authors:  Ashraf M Khalil; John C Cambier; Mark J Shlomchik
Journal:  Science       Date:  2012-05-03       Impact factor: 47.728

8.  Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation.

Authors:  Nadine Bollig; Anne Brüstle; Kerstin Kellner; Waltraud Ackermann; Elfadil Abass; Hartmann Raifer; Bärbel Camara; Cornelia Brendel; Gavin Giel; Evita Bothur; Magdalena Huber; Christoph Paul; Alexandra Elli; Richard A Kroczek; Roza Nurieva; Chen Dong; Ralf Jacob; Tak W Mak; Michael Lohoff
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-02       Impact factor: 11.205

9.  Clonal selection in the germinal centre by regulated proliferation and hypermutation.

Authors:  Alexander D Gitlin; Ziv Shulman; Michel C Nussenzweig
Journal:  Nature       Date:  2014-05-04       Impact factor: 49.962

10.  A theory of germinal center B cell selection, division, and exit.

Authors:  Michael Meyer-Hermann; Elodie Mohr; Nadége Pelletier; Yang Zhang; Gabriel D Victora; Kai-Michael Toellner
Journal:  Cell Rep       Date:  2012-06-28       Impact factor: 9.423
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  355 in total

1.  IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice.

Authors:  Huixian Hong; Min Gao; Qi Wu; PingAr Yang; Shanrun Liu; Hao Li; Peter D Burrows; Daniel Cua; Jake Y Chen; Hui-Chen Hsu; John D Mountz
Journal:  J Immunol       Date:  2020-06-17       Impact factor: 5.422

Review 2.  Itch regulation of innate and adaptive immune responses in mice and humans.

Authors:  Natania S Field; Emily K Moser; Paula M Oliver
Journal:  J Leukoc Biol       Date:  2020-04-30       Impact factor: 4.962

3.  Intrinsic properties of human germinal center B cells set antigen affinity thresholds.

Authors:  Kihyuck Kwak; Nicolas Quizon; Haewon Sohn; Avva Saniee; Javier Manzella-Lapeira; Prasida Holla; Joseph Brzostowski; Jinghua Lu; HengYi Xie; Chenguang Xu; Katelyn M Spillane; Pavel Tolar; Susan K Pierce
Journal:  Sci Immunol       Date:  2018-11-30

4.  Differential interactions of missing in metastasis and insulin receptor tyrosine kinase substrate with RAB proteins in the endocytosis of CXCR4.

Authors:  Lushen Li; Shaneen S Baxter; Peng Zhao; Ning Gu; Xi Zhan
Journal:  J Biol Chem       Date:  2019-02-26       Impact factor: 5.157

5.  Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity.

Authors:  Christopher W Farnsworth; Eric M Schott; Abigail Benvie; Stephen L Kates; Edward M Schwarz; Steven R Gill; Michael J Zuscik; Robert A Mooney
Journal:  J Immunol       Date:  2018-06-01       Impact factor: 5.422

6.  B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells.

Authors:  Wei Luo; Florian Weisel; Mark J Shlomchik
Journal:  Immunity       Date:  2018-02-20       Impact factor: 31.745

7.  TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.

Authors:  Pilar M Dominguez; Hussein Ghamlouch; Wojciech Rosikiewicz; Parveen Kumar; Wendy Béguelin; Lorena Fontán; Martín A Rivas; Patrycja Pawlikowska; Marine Armand; Enguerran Mouly; Miguel Torres-Martin; Ashley S Doane; María T Calvo Fernandez; Matt Durant; Veronique Della-Valle; Matt Teater; Luisa Cimmino; Nathalie Droin; Saber Tadros; Samaneh Motanagh; Alan H Shih; Mark A Rubin; Wayne Tam; Iannis Aifantis; Ross L Levine; Olivier Elemento; Giorgio Inghirami; Michael R Green; Maria E Figueroa; Olivier A Bernard; Said Aoufouchi; Sheng Li; Rita Shaknovich; Ari M Melnick
Journal:  Cancer Discov       Date:  2018-10-01       Impact factor: 39.397

8.  Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells.

Authors:  Michael Boice; Darin Salloum; Frederic Mourcin; Viraj Sanghvi; Rada Amin; Elisa Oricchio; Man Jiang; Anja Mottok; Nicolas Denis-Lagache; Giovanni Ciriello; Wayne Tam; Julie Teruya-Feldstein; Elisa de Stanchina; Wing C Chan; Sami N Malek; Daisuke Ennishi; Renier J Brentjens; Randy D Gascoyne; Michel Cogné; Karin Tarte; Hans-Guido Wendel
Journal:  Cell       Date:  2016-09-29       Impact factor: 41.582

9.  Suppression by TFR cells leads to durable and selective inhibition of B cell effector function.

Authors:  Peter T Sage; Noga Ron-Harel; Vikram R Juneja; Debattama R Sen; Seth Maleri; Waradon Sungnak; Vijay K Kuchroo; W Nicholas Haining; Nicolas Chevrier; Marcia Haigis; Arlene H Sharpe
Journal:  Nat Immunol       Date:  2016-10-03       Impact factor: 25.606

10.  Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders.

Authors:  Diana Ahmetspahic; Kathrin Schwarte; Oliver Ambrée; Christian Bürger; Vladislava Falcone; Katharina Seiler; Mehrdad Rahbar Kooybaran; Laura Grosse; Fernand Roos; Julia Scheffer; Silke Jörgens; Katja Koelkebeck; Udo Dannlowski; Volker Arolt; Stefanie Scheu; Judith Alferink
Journal:  J Neuroimmune Pharmacol       Date:  2017-09-13       Impact factor: 4.147
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