Literature DB >> 2565585

A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia.

K S Vaddadi1, P Courtney, C J Gilleard, M S Manku, D F Horrobin.   

Abstract

This study reports the results of a trial of essential fatty acid (EFA) supplementation in psychiatric patients (predominantly schizophrenics) with movement disorders. Evidence of EFA deficiency in these patients was observed. The antidyskinetic effect of EFA supplementation was marginally significant but not clinically important. However, active treatment produced highly significant improvements in total psychopathology scores and schizophrenia subscale scores, and a significant improvement in memory.

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Year:  1989        PMID: 2565585     DOI: 10.1016/0165-1781(89)90146-7

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  8 in total

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Authors:  Elizabeth M Williamson
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

Review 3.  Oxidative damage and schizophrenia: an overview of the evidence and its therapeutic implications.

Authors:  J K Yao; R D Reddy; D P van Kammen
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 4.  Polyunsaturated fatty acid supplementation for schizophrenia.

Authors:  C B Joy; R Mumby-Croft; L A Joy
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

5.  High levels of dietary arachidonic acid triglyceride exhibit no subchronic toxicity in rats.

Authors:  E K Koskelo; K Boswell; L Carl; S Lanoue; C Kelly; D Kyle
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6.  Update and critique of natural remedies as antidepressant treatments.

Authors:  David Mischoulon
Journal:  Obstet Gynecol Clin North Am       Date:  2009-12       Impact factor: 2.844

Review 7.  Miscellaneous treatments for antipsychotic-induced tardive dyskinesia.

Authors:  Karla Soares-Weiser; John Rathbone; Yusuke Ogawa; Kiyomi Shinohara; Hanna Bergman
Journal:  Cochrane Database Syst Rev       Date:  2018-03-19

8.  Natural Medicines for Psychotic Disorders: A Systematic Review.

Authors:  H J Rogier Hoenders; Agna A Bartels-Velthuis; Nina K Vollbehr; Richard Bruggeman; Henderikus Knegtering; Joop T V M de Jong
Journal:  J Nerv Ment Dis       Date:  2018-02       Impact factor: 2.254

  8 in total

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