| Literature DB >> 2565419 |
A Palotie1, P Väisänen, J Ott, L Ryhänen, K Elima, M Vikkula, K Cheah, E Vuorio, L Peltonen.
Abstract
The genetic background of two families, in whom a predisposition to primary osteoarthrosis is inherited as a dominant trait, was investigated. Use of restriction fragment length polymorphisms within and around the type II collagen gene on chromosome 12 revealed a linkage between this cartilage-specific gene and primary osteoarthrosis.Entities:
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Year: 1989 PMID: 2565419 DOI: 10.1016/s0140-6736(89)92507-5
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321