Madhu Bhatia1, Shilpa Sarvesh Urolagin2, Kishore Babu Pentyala3, Sarvesh Basavaraj Urolagin4, Menaka K B5, Shreedevi Bhoi6. 1. Private Practioner, Department of Periodontics, New you Cosmetic Clinic , Bangalore, Karnataka, India . 2. Lecturer, Department of Periodontics, Narsinhbhai Patel Dental College , North Gujarat, India. 3. Private Practioner, Department of Oral & Maxillofacial Surgery, New you Cosmetic Clinic , Bangalore, Karnataka, India . 4. Reader, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India . 5. Reader, Department of Periodontics, KLE V. K. Institute of Dental Sciences , Belgaum, Karnataka, India . 6. Lecturer, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India .
Abstract
AIMS AND OBJECTIVES: The aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis. MATERIALS AND METHODS: The study group consisted of 25 patients, belonging to both sex, aged between 21-45 years. All patients diagnosed as chronic periodontitis with periodontal pockets of depth >5mm bilaterally were randomly selected. A split mouth design was followed and the patients received a complete prophylaxis including scaling and root planing. Examination of plaque index, bleeding index, probing pocket depth and clinical attachment level were measured for each patient. The test group received 1% curcumin gel along with scaling and root planing whereas the control group received scaling and root planing alone followed by microbiological samples taken at baseline, 1, 3 and 6 months interval. RESULTS: The 1% curcumin gel appeared to provide significant improvements in clinical parameters. Microbiological counts of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and capnocytophaga showed significant reduction in periopathogens at the test sites after six months when compared with that of control sites. CONCLUSION: Locally delivered 1% curcumin gel was more effective in inhibiting the growth of oral bacteria when used as an adjunct to SRP in the treatment of chronic periodontitis.
AIMS AND OBJECTIVES: The aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis. MATERIALS AND METHODS: The study group consisted of 25 patients, belonging to both sex, aged between 21-45 years. All patients diagnosed as chronic periodontitis with periodontal pockets of depth >5mm bilaterally were randomly selected. A split mouth design was followed and the patients received a complete prophylaxis including scaling and root planing. Examination of plaque index, bleeding index, probing pocket depth and clinical attachment level were measured for each patient. The test group received 1% curcumin gel along with scaling and root planing whereas the control group received scaling and root planing alone followed by microbiological samples taken at baseline, 1, 3 and 6 months interval. RESULTS: The 1% curcumin gel appeared to provide significant improvements in clinical parameters. Microbiological counts of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and capnocytophaga showed significant reduction in periopathogens at the test sites after six months when compared with that of control sites. CONCLUSION: Locally delivered 1% curcumin gel was more effective in inhibiting the growth of oral bacteria when used as an adjunct to SRP in the treatment of chronic periodontitis.
Entities:
Keywords:
Curcumin; Local drug delivery; Periodontitis
Authors: J J Escobar-Chávez; M López-Cervantes; A Naïk; Y N Kalia; D Quintanar-Guerrero; A Ganem-Quintanar Journal: J Pharm Pharm Sci Date: 2006 Impact factor: 2.327
Authors: Sanjeela Rakshith Guru; K Adithya Reddy; Ravi J Rao; Shyam Padmanabhan; Rakshith Guru; T S Srinivasa Journal: J Indian Soc Periodontol Date: 2020-05-04